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2048 Ventures is an early-stage venture capital firm that primarily invests in pre-seed and seed rounds. They focus on thesis-driven investments in Vertical AI, Deep Tech Infrastructure, Healthcare, and Biotech, seeking companies that build defensibility through data and technology, often as "Systems of Record" or API platforms.
They made 1 investments in the last 12 months. Their most common stage is seed (54% of deals). Average disclosed round size is $16.3M (across 13 rounds with reported amounts).
Portfolio
13
Fund Size
$82M
Top Stage
Seed
Last 12 Mo
1
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
13 investments
| Company | Round | Amount | Date |
|---|---|---|---|
| Seed | $3.3M | Aug 2025 | |
| Seed | $4M | Aug 2023 | |
| FFemTherapeutics | Seed | $1.9M | May 2023 |
| Seed | $2M | Mar 2023 | |
| Seed | $2.5M | Nov 2022 | |
| Series A | $110M | May 2022 | |
| Series B | $35M | Jan 2022 | |
| Series A | $10.8M | Oct 2021 | |
| Series A | $15M | Jul 2021 | |
| Series A | $10M | May 2021 | |
| Series A | $8M | Feb 2021 | |
| Seed | $2.5M | Oct 2020 | |
| Seed | $6.8M | — |
Top Co-Investors
Matchstick Ventures3 shared
Y Combinator2 shared
Knoll Ventures2 shared
Techstars2 shared
Bloomberg Beta1 shared
FirstMark Capital1 shared
GitHub1 shared
Seamless1 shared
Stripe1 shared
Dynamo1 shared
Underscore VC1 shared
Uncorrelated Ventures1 shared
I2BF1 shared
Hack VC1 shared
Navitas1 shared
Altos Ventures1 shared
Indicator Ventures1 shared
Detroit Venture Partners1 shared
Hustle Fund1 shared
Union Square Ventures1 shared
Last updated: 16 April 2026