Impact Science Ventures (ISV) is an early-stage venture capital firm that invests in fundamental scientific breakthroughs and deep-tech innovations across critical sectors including energy, biotech, materials, manufacturing, and agriculture. The firm is based in San Francisco, California.
48% of their portfolio is in Climate & Energy. They made 1 investment in the last 12 months. Average disclosed round size is $121.9M (across 22 rounds with reported amounts).
Portfolio
19
Fund Size
—
Top Stage
Seed
Last 12 Mo
1
Team
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
23 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 Sepion Technologies | Series B | $10M | Jan 2026 |
| FFervo | Series E | $462M | Dec 2025 |
 Fervo Energy | Bridge | $462M | Jan 2025 |
 Aepnus | Seed | $8M | Jun 2024 |
| Aepnus | Seed | $8M | Jun 2024 |
| Fervo Energy | Series C | — | Feb 2024 |
| DDevon Energy | Series C | $244M | Jan 2024 |
 Qunnect | Series A | $8M | Oct 2022 |
 Antora Energy | Series C | $550M | Feb 2022 |
| Fervo Energy | Series E | $138M | Jan 2022 |
| Sepion Technologies | Series A | $16M | Jan 2021 |
 Still Bright | Seed | $18.7M | — |
 Liminal | Unknown | $17.5M | — |
 Brimstone | Unknown | $55M | — |
 Antora | Series C | $550M | — |
 Aralez Bio | Series A | $12M | — |
 Sun Metalon | Series A | $21M | — |
 AirMyne | Seed | $6.9M | — |
 Copernic Catalysts | Seed | $8M | — |
 Liminal Insights | Unknown | $17.5M | — |
 Copernic | Seed | $8M | — |
 Brimstone Energy | Series A | $55M | — |
| MMafix | Pre-Seed | $5.4M | — |
Top Co-Investors
Breakthrough Energy Ventures9 shared
DCVC7 shared
Marunouchi Innovation Partners5 shared
Mitsubishi Heavy Industries5 shared
Congruent Ventures5 shared
Liberty Mutual4 shared
Lowercarbon Capital4 shared
Sabanci Climate Ventures4 shared
B Capital4 shared
Capricorn Investment Group4 shared
Elemental Excelerator3 shared
Good Growth Capital3 shared
Mitsui & Co3 shared
Galvanize Climate Solutions2 shared
Macquarie Capital2 shared
Prelude Ventures2 shared
Liberty Energy Capital2 shared
Airbus Ventures2 shared
Azolla Ventures2 shared
Last updated: 27 September 2026