Plaisance Capital Management
Cambridge, Massachusetts, United StatesFounded 2020
Plaisance Capital Management is a biotech-focused investment management company founded in 2020 and based in Cambridge, Massachusetts. It discovers, nurtures, and invests in promising biotechnology startups, providing them with resources, mentorship, and capital.
57% of their portfolio is in Biotech & Life Sciences. Average disclosed round size is $71.9M (across 7 rounds with reported amounts).
Portfolio
6
Fund Size
—
Top Stage
Series C
Last 12 Mo
1
Team
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
7 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 BlossomHill Therapeutics | Series B | $84M | Dec 2025 |
 Full-Life Technologies | Series C | $50M | Sep 2025 |
 Reunion Neuroscience | Series A | $103M | May 2024 |
 Stellaromics | Series A | $25M | Nov 2023 |
 Corsair Pharma | Series B | $23M | Sep 2023 |
 Iaso Biotherapeutics | Series C | $108M | Sep 2021 |
| Full-Life Technologies | Series D | $110M | — |
Top Co-Investors
Junson Capital3 shared
InnoVen Capital2 shared
Chengwei Capital2 shared
Vivo Capital2 shared
Lam Capital1 shared
Giant Ventures1 shared
Summer Capital1 shared
Prosperity7 Ventures1 shared
HongShan1 shared
Stanford University1 shared
Cormorant Asset Management1 shared
OrbiMed1 shared
Janus Henderson Investors1 shared
Brahma Capital1 shared
BioTrack Capital1 shared
W Health Ventures1 shared
Palo Santo1 shared
Arkin Bio Ventures1 shared
MPM Capital1 shared
Last updated: 20 October 2026