Plaisance Capital Management
Cambridge, Massachusetts, United StatesFounded 2020
Plaisance Capital Management is a biotech-focused investment management company founded in 2020 and based in Cambridge, Massachusetts. It discovers, nurtures, and invests in promising biotechnology startups, providing them with resources, mentorship, and capital.
67% of their portfolio is in Biotech & Life Sciences. They made 2 investments in the last 12 months. Average disclosed round size is $65.5M (across 6 rounds with reported amounts).
Portfolio
6
Fund Size
—
Top Stage
Series C
Last 12 Mo
2
Team
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
6 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 BlossomHill Therapeutics | Series B | $84M | Dec 2025 |
 Full-Life Technologies | Series C | $50M | Sep 2025 |
 Reunion Neuroscience | Series A | $103M | May 2024 |
 Stellaromics | Series A | $25M | Nov 2023 |
 Corsair Pharma | Series B | $23M | Sep 2023 |
 Iaso Biotherapeutics | Series C | $108M | Sep 2021 |
Top Co-Investors
Junson Capital2 shared
Chengwei Capital1 shared
Lam Capital1 shared
Giant Ventures1 shared
Summer Capital1 shared
Prosperity7 Ventures1 shared
HongShan1 shared
Cormorant Asset Management1 shared
OrbiMed1 shared
Vivo Capital1 shared
Brahma Capital1 shared
BioTrack Capital1 shared
W Health Ventures1 shared
Palo Santo1 shared
Arkin Bio Ventures1 shared
MPM Capital1 shared
Novo Holdings A/S1 shared
New Rhein Healthcare Investors1 shared
Primavera Capital Group1 shared
Last updated: 14 September 2026