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    Signet Healthcare Partners

    New York, New York, United StatesFounded 1998

    Signet Healthcare Partners is a New York-based growth equity firm founded in 1998 that provides growth capital to innovative, commercial-stage healthcare companies. The firm focuses on specialty pharmaceuticals, pharmaceutical services, medical devices, and diagnostics, with typical investments of $10-50 million.

    Average disclosed round size is $32.7M (across 8 rounds with reported amounts).

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    Portfolio

    11

    Fund Size

    $137.2M

    Top Stage

    Series B

    Last 12 Mo

    0

    Team

    JG

    James Gale

    Founding Partner & Managing Director

    AF

    Ashley Friedman

    Managing Director

    NP

    Nikhil Puri

    Managing Director

    JS

    Jaime Sosa

    Director of Finance

    EP

    Emad Piracha

    Vice President

    AL

    Audrey Liu

    Associate

    LH

    Louise Hamilton

    Executive Assistant

    VW

    Vladimir Walko

    Portfolio Breakdown

    Stage Distribution

    Sector Distribution

    Investment Activity

    DealsAvg Round Size

    Portfolio

    13 investments
    CompanyRoundAmountDate
    PParagonix TechnologiesSeries B$24MJan 2023
    Leon Nanodrugs logoLeon NanodrugsSeries B—Apr 2020
    Smart Medical Systems Ltd. logoSmart Medical Systems Ltd.Series B$8MFeb 2018
    LLeading PharmaGrowth$40MJan 2018
    PPharmaceutics International Inc. (Pii)Unknown$93MJan 2016
    CChr. Olesen SynthesisSeries A—Oct 2015
    Leon Nanodrugs logoLeon NanodrugsSeries A—Jul 2015
    Arbor Pharmaceuticals logoArbor PharmaceuticalsSeries B$34.8MNov 2010
    PPEAK SurgicalSeries C$21MFeb 2008
    BBioject Medical TechnologiesUnknown$600KDec 2007
    DDirevo BiotechSeries C—Oct 2007
    AAlpex PharmaSeries B——
    LLeading PharmaGrowth$40M—

    Top Co-Investors

    Last updated: 20 October 2026