Wireframe Ventures is a pre-seed and seed-stage venture capital firm based in San Francisco that backs missionary founders using technology to improve the health of people and the planet. The firm closed its Fund II at $77M, focusing on climate and health themes.
Deal activity decreased year-over-year (2 deals in the last 12 months vs 4 prior). Average disclosed round size is $20.7M (across 31 rounds with reported amounts).
Portfolio
28
Fund Size
$77M
Top Stage
Seed
Last 12 Mo
2
Team
HP
Harsh P.
Managing Partner & Co-Founder
PS
Paul Straub
Managing Partner & Co-Founder
LB
Lily Bernicker
Partner
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
33 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 Sora Fuel | Series A | $14.6M | Apr 2026 |
 C.SCALE | Pre-Seed | $2M | Nov 2025 |
 Tyba | Series A | $13.9M | Feb 2025 |
 Climate Robotics | Series A | $21.5M | Aug 2024 |
 Applied Carbon | Series A | $21.5M | Jul 2024 |
 Tembo Inc | Series A | $14M | Jul 2024 |
| Climate Robotics | Series A | $21.5M | Jan 2024 |
 Gridware | Seed | $10.5M | Jun 2023 |
 Xcimer Energy | Seed | $100M | Jan 2023 |
 Zivian Health | Seed | $3M | Jan 2023 |
 Synop | Seed | $10M | Jun 2022 |
| SSolo AVT | Seed | $7M | Mar 2022 |
 Phytoform | Seed | $5.7M | Dec 2021 |
 Recurrent | Seed | $3.5M | Dec 2020 |
 MycoWorks | Series B | $45M | Nov 2020 |
 Endpoint Health | Unknown | — | Jul 2020 |
 Electriphi | Unknown | $3.5M | Feb 2020 |
| EElectriphi Ai | Unknown | $3.5M | Feb 2020 |
| Electriphi | Seed | $3.5M | Jan 2020 |
| MycoWorks | Series A | $17M | Dec 2019 |
 Astronomer | Seed | $5.7M | Sep 2019 |
 Cocoon | Pre-Seed | $5.4M | — |
 LevelTen Energy | Unknown | $6.8M | — |
 Cocoon Carbon | Series A | $15M | — |
 OpenInvest | Series A | $10.4M | — |
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Top Co-Investors
Prelude Ventures4 shared
Congruent Ventures4 shared
Gigascale Capital4 shared
SOSV3 shared
Powerhouse Ventures3 shared
Lowercarbon Capital3 shared
Y Combinator3 shared
Anglo American3 shared
S2G Ventures3 shared
Grantham Foundation3 shared
TELUS Pollinator Fund for Good3 shared
Crosslink Capital3 shared
Lemnos3 shared
Blackhorn Ventures3 shared
Urban Innovation Fund3 shared
8VC2 shared
DCVC2 shared
AgFunder2 shared
Novo Holdings A/S2 shared
Last updated: 8 September 2026