Wireframe Ventures is a pre-seed and seed-stage venture capital firm based in San Francisco that backs missionary founders using technology to improve the health of people and the planet. The firm closed its Fund II at $77M, focusing on climate and health themes.
Deal activity increased 100% year-over-year (2 deals in the last 12 months). Average disclosed round size is $18.3M (across 49 rounds with reported amounts).
Portfolio
38
Fund Size
$77M
Top Stage
Seed
Last 12 Mo
2
Team
HP
Harsh P.
Managing Partner & Co-Founder
PS
Paul Straub
Managing Partner & Co-Founder
LB
Lily Bernicker
Partner
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
52 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 Sora Fuel | Series A | $14.6M | Apr 2026 |
 C.SCALE | Pre-Seed | $2M | Nov 2025 |
 Tyba | Series A | $13.9M | Feb 2025 |
 Climate Robotics | Series A | $21.5M | Aug 2024 |
 Applied Carbon | Series A | $21.5M | Jul 2024 |
 SirenOpt | Seed | $6.6M | Jul 2024 |
 Tembo Inc | Series A | $14M | Jul 2024 |
| Climate Robotics | Series A | $21.5M | Jan 2024 |
| Sora Fuel | Seed | $6M | Jan 2024 |
 Caladan Bio | Seed | $5M | Jan 2024 |
 Gridware | Seed | $10.5M | Jun 2023 |
 Xcimer Energy | Seed | $100M | Jan 2023 |
 Zivian Health | Seed | $3M | Jan 2023 |
 Synop | Seed | $10M | Jun 2022 |
| SSolo AVT | Seed | $7M | Mar 2022 |
| Synop | Unknown | $10M | Jan 2022 |
 Phytoform Labs | Seed | $5.7M | Dec 2021 |
 Cocoon | Series A | $20M | Sep 2021 |
 Near Space Labs | Unknown | $13M | Sep 2021 |
 Near Space Labs | Unknown | $13M | Sep 2021 |
| LLevelTen | Series C | $35M | Aug 2021 |
| Near Space Labs | Series A | $13M | Jan 2021 |
 Recurrent | Seed | $3.5M | Dec 2020 |
 MycoWorks | Series B | $45M | Nov 2020 |
 Endpoint Health | Unknown | — | Jul 2020 |
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Top Co-Investors
Prelude Ventures7 shared
Y Combinator6 shared
Gigascale Capital6 shared
Crosslink Capital6 shared
SOSV5 shared
Congruent Ventures5 shared
Powerhouse Ventures4 shared
Techstars4 shared
Lowercarbon Capital3 shared
True Ventures3 shared
Pioneer Square Labs3 shared
Anglo American3 shared
S2G Ventures3 shared
Overture VC3 shared
Grantham Foundation3 shared
TELUS Pollinator Fund for Good3 shared
First Star Ventures3 shared
Lemnos3 shared
Blackhorn Ventures3 shared
Last updated: 20 October 2026