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    Investment Firms in Brussels, Belgium

    As the capital of the European Union, it serves as a strategic hub for policy-influenced startups and venture capital, particularly in healthcare and deep tech. The ecosystem benefits from strong connections to multinational institutions and research universities, fostering innovation in sectors like artificial intelligence and semiconductors. Venture activity is characterized by a mature investment landscape, with significant capital often deployed in the Series A stage and beyond.

    Brussels, Belgium's investment landscape is shaped by Healthcare, with 56% of its 19 investment firms focused on this sector. The most active by portfolio size are European Innovation Council (EIC), PMV, and Sofina.

    Healthcare dominates the investment landscape in Brussels, with 56% of investment firms focused on this sector.

    Brussels is a particularly strong hub for early-stage investing, with over 84% of investment firms active at the Seed or Pre-Seed stage.

    Last updated: 9 September 2026

    Investment Firms

    19

    Total Investments

    526

    Top Sector

    Healthcare

    Top Stage

    Series A

    Top Investment Sectors in Brussels

    The most popular sector focus among Brussels investment firms is Healthcare, with 10 investment firms (53%) investing in the space. This is followed by Climate & Energy (9), Biotech & Life Sciences (8), Food & Agriculture (5), AI (4).

    Investment Stages in Brussels

    Brussels investment firms are most active at the Series A stage (15 investment firms). This is followed by Seed (15), Series B (14), Growth (12), Series C (10).

    European Innovation Council (EIC) logo

    European Innovation Council (EIC)

    Brussels, Belgium

    196 investments

    Series A, Seed

    AI, Biotech & Life Sciences, Climate & Energy

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    PMV logo

    PMV

    Brussels, Belgium

    70 investments

    Series A, Seed

    Biotech & Life Sciences, Climate & Energy, Enterprise Software

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    Sofina logo

    Sofina

    Brussels, Belgium

    50 investments

    Series D, Series C

    Consumer, Education, Food & Agriculture

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    Verlinvest logo

    Verlinvest

    Brussels, Belgium

    26 investments

    Series A, Series C

    Consumer, Food & Agriculture, Healthcare

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    Smartfin logo

    Smartfin

    Brussels, Belgium

    23 investments

    Series A, Seed

    Enterprise Software, Fintech, SaaS

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    UCB logo

    UCB

    Brussels, Belgium

    17 investments

    Series B, Series A

    Biotech & Life Sciences, Healthcare

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    Syndicate One logo

    Syndicate One

    Brussels, Belgium

    16 investments

    Seed, Pre Seed

    Enterprise Software, Cybersecurity, Fintech

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    Seeder logo

    Seeder

    Brussels, Belgium

    16 investments

    Seed, Pre Seed

    SaaS, Fintech, Enterprise Software

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    SFPIM logo

    SFPIM

    Brussels, Belgium

    15 investments

    Series A, Series B

    Biotech & Life Sciences, Healthcare, Infrastructure & Cloud

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    Tioga Capital logo

    Tioga Capital

    Brussels, Belgium

    13 investments

    Series A, Seed

    Crypto & Web3

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    Newton Biocapital logo

    Newton Biocapital

    Brussels, Belgium

    13 investments

    Series A, Series B

    Biotech & Life Sciences, Healthcare

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    ScaleFund logo

    ScaleFund

    Brussels, Belgium

    11 investments

    Seed, Pre Seed

    Climate & Energy, SaaS

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    Edaphon logo

    Edaphon

    Brussels, Belgium

    11 investments

    Series A, Series B

    Food & Agriculture, Climate & Energy, Biotech & Life Sciences

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    European Commission logo

    European Commission

    Brussels, Belgium

    11 investments

    Seed

    AI, Biotech & Life Sciences, Climate & Energy

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    Bioqube Ventures logo

    Bioqube Ventures

    Brussels, Belgium

    10 investments

    Series A, Seed

    Biotech & Life Sciences, Healthcare

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    KBC Focus Fund logo

    KBC Focus Fund

    Brussels, Belgium

    9 investments

    Series A, Seed

    Manufacturing, Data & Analytics

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    BNP Paribas Fortis Private Equity logo

    BNP Paribas Fortis Private Equity

    Brussels, Belgium

    7 investments

    Series A, Series C

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    SPDG logo

    SPDG

    Brussels, Belgium

    7 investments

    Growth, Seed

    Mobility & Transportation, Climate & Energy, Infrastructure & Cloud

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    Newtree Impact logo

    Newtree Impact

    Brussels, Belgium

    5 investments

    Series B, Pre Seed

    Food & Agriculture, Climate & Energy

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