Investment Firms in San Francisco, California, United States
Long established as the global epicenter of venture capital, this city is distinguished by its unparalleled concentration of investors, serial entrepreneurs, and technical talent. Its ecosystem is deeply intertwined with world-renowned research universities and a historical legacy of pioneering the technology and internet industries. The investment focus remains sharply on frontier sectors like artificial intelligence, fintech, and biotechnology.
One of the world's premier venture capital hubs, San Francisco, California, United States is home to 471 investment firms tracked by Goldilocks AI, with a combined portfolio of over 26,158 investments spanning from established leaders like Y Combinator to newer entrants like Seven Stars.
AI dominates the investment landscape in San Francisco, with 49% of investment firms focused on this sector.
San Francisco is a particularly strong hub for early-stage investing, with over 90% of investment firms active at the Seed or Pre-Seed stage.
Last updated: 20 October 2026
Investment Firms
471
Total Investments
26,158
Top Sector
AI
Top Stage
Series A
Top Investment Sectors in San Francisco
The most popular sector focus among San Francisco investment firms is AI, with 225 investment firms (48%) investing in the space. This is followed by Enterprise Software (187), Fintech (186), Healthcare (179), SaaS (153).
Investment Stages in San Francisco
San Francisco investment firms are most active at the Series A stage (440 investment firms). This is followed by Seed (426), Series B (351), Pre-Seed (250), Series C (227).
Showing 1–36 of 471 investment firms
Y Combinator
San Francisco, California, United States
2,557 investments
Seed, Series A
AI, Biotech & Life Sciences, Climate & Energy …
General Catalyst
San Francisco, California, United States
983 investments
Seed, Series A
AI, Healthcare, Fintech …
Founders Fund
San Francisco, California, United States
704 investments
Series A, Seed
Defense & Space, AI, Biotech & Life Sciences …
GV (Google Ventures)
San Francisco, California, United States
695 investments
Series A, Series B
AI, Biotech & Life Sciences, Climate & Energy …
SV Angel
San Francisco, California, United States
543 investments
Seed, Series A
AI, Enterprise Software
First Round
San Francisco, California, United States
435 investments
Seed, Series A
AI, Consumer, Enterprise Software …
Salesforce Ventures
San Francisco, California, United States
430 investments
Series B, Series C
AI, Enterprise Software, SaaS …
Coinbase Ventures
San Francisco, California, United States
358 investments
Seed, Series A
Crypto & Web3, Fintech
Bain Capital Ventures
San Francisco, California, United States
336 investments
Series B, Series A
Fintech, AI, Cybersecurity …
Soma Capital
San Francisco, California, United States
294 investments
Seed, Series A
SaaS, Enterprise Software, AI …
Matrix
San Francisco, California, United States
284 investments
Series A, Series B
AI, Fintech, Enterprise Software …
Liquid 2 Ventures
San Francisco, California, United States
241 investments
Seed, Series A
Enterprise Software, AI, Developer Tools …
Initialized Capital
San Francisco, California, United States
227 investments
Seed, Series A
AI, Consumer, Crypto & Web3 …
Craft Ventures
San Francisco, California, United States
214 investments
Series A, Seed
SaaS, E-Commerce & Marketplace, Enterprise Software …
Headline
San Francisco, California, United States
209 investments
Series A, Series B
Consumer, Enterprise Software, SaaS
B Capital
San Francisco, California, United States
206 investments
Series A, Series B
AI, Enterprise Software, Fintech …
Slow Ventures
San Francisco, California, United States
204 investments
Seed, Series A
AI, Consumer, Crypto & Web3 …
M12 (Microsoft)
San Francisco, California, United States
203 investments
Series A, Series B
AI, Enterprise Software, Cybersecurity …
Crosslink Capital
San Francisco, California, United States
203 investments
Series A, Seed
Data & Analytics, Infrastructure & Cloud, Fintech …
Village Global
San Francisco, California, United States
203 investments
Seed, Series A
AI, Consumer, Fintech …
Benchmark
San Francisco, California, United States
202 investments
Series A, Series B
AI, E-Commerce & Marketplace, Infrastructure & Cloud …
Gradient
San Francisco, California, United States
193 investments
Seed, Series A
AI, Developer Tools, Enterprise Software …
Abstract
San Francisco, California, United States
190 investments
Seed, Series A
ICONIQ Capital
San Francisco, California, United States
186 investments
Series C, Series B
AI, Consumer, Enterprise Software …
Pioneer Fund
San Francisco, California, United States
176 investments
Seed, Series A
AI, SaaS, Fintech …
NFX
San Francisco, California, United States
172 investments
Seed, Series A
AI, Biotech & Life Sciences, Consumer …
SignalFire
San Francisco, California, United States
168 investments
Series A, Series B
AI, Enterprise Software, Cybersecurity …
Bloomberg Beta
San Francisco, California, United States
164 investments
Series A, Seed
AI, Data & Analytics, Enterprise Software …
Kindred Ventures
San Francisco, California, United States
160 investments
Seed, Series A
AI, Climate & Energy, Consumer …
Precursor Ventures
San Francisco, California, United States
155 investments
Seed, Series A
Consumer, Enterprise Software, Fintech …
Pantera Capital
San Francisco, California, United States
155 investments
Seed, Series A
Crypto & Web3, Fintech
Polychain Capital
San Francisco, California, United States
154 investments
Seed, Series A
Crypto & Web3
Forerunner Ventures
San Francisco, California, United States
150 investments
Series A, Seed
Consumer, E-Commerce & Marketplace, Healthcare
Susa Ventures
San Francisco, California, United States
148 investments
Seed, Series A
AI, Fintech, Healthcare …
Tribe Capital
San Francisco, California, United States
140 investments
Series B, Seed
AI, Crypto & Web3, Fintech …
Versant Ventures
San Francisco, California, United States
140 investments
Series A, Series B
Biotech & Life Sciences, Healthcare
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