Ascension Ventures (AV) is the strategic healthcare venture capital arm of Ascension Health, based in Clayton, Missouri. Founded in 2001, it invests in healthcare technology, services, medical devices, and diagnostics from early to late stage. Its latest fund, CHV V, closed at $285 million in 2021, bringing total assets under management to more than $1 billion.
Deal activity decreased year-over-year (3 deals in the last 12 months vs 9 prior). Average disclosed round size is $42.1M (across 91 rounds with reported amounts).
Portfolio
114
Fund Size
$285M
Top Stage
Seed
Last 12 Mo
3
Team
Sean Cheng, PhD
Managing Director
Emily Kuhns
Finance Director
Kate Davis
Investment Principal
Guneesh Batra
Investment Manager
Jamie Wehrung
Chief Administrative Officer
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
Portfolio
| Company | Round | Amount | Date |
|---|---|---|---|
 Saltroad | Pre-Seed | — | Jun 2026 |
 Manamind | Pre-Seed | — | Apr 2026 |
 Kinfolk | Seed | $7.2M | Feb 2026 |
 Stream | Series D | $90M | Jan 2026 |
| NNeuronostics | Seed | — | Jan 2026 |
 ComplyStream | Pre-Seed | — | Apr 2025 |
 Sprive | Series A | $7.3M | Apr 2025 |
 Capably | Seed | $4M | Apr 2025 |
 Linq | Pre-Seed | — | Mar 2025 |
 Wagestream | Series D | $90M | Jan 2025 |
 Hesta Health | Pre-Seed | — | Jan 2025 |
 Cala Health | Growth | $50M | Dec 2024 |
 Tembo Inc | Series B | — | Nov 2024 |
| RResearch Grid (R.grid) | Seed | $6.5M | Nov 2024 |
 Round Treasury | Pre-Seed | — | Oct 2024 |
 CSA Medical | Series D | $53M | Sep 2024 |
 Zen Educate | Series B | $37M | May 2024 |
 Healthkey | Seed | $1.4M | Apr 2024 |
 Qureight | Series A | — | Apr 2024 |
 R.grid | Seed | $6.5M | Jan 2024 |
 NumberEight | Series A | $2.7M | Jan 2024 |
 Xgenera | Unknown | — | Jan 2024 |
| Zen Educate | Series B | $37M | Jan 2024 |
 Zen | Series B | $37M | Jan 2024 |
 Censys | Series C | $75M | Oct 2023 |
Top Co-Investors
Last updated: 7 October 2026