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    Chemistry

    San Francisco, California, United StatesFounded 2024

    Chemistry is a $350M early-stage venture firm founded by Mark Goldberg, Kristina Shen, and Ethan Kurzweil. It leads investments in standout software companies from Seed through Series A, backing founders who blend technical expertise with commercial instincts.

    Deal activity increased 400% year-over-year (10 deals in the last 12 months). Their most common stage is series-a (61% of deals). Average disclosed round size is $51.7M (across 29 rounds with reported amounts).

    Find people at Chemistry on Goldilocks AI

    Portfolio

    20

    Fund Size

    $350M

    Top Stage

    Series A

    Last 12 Mo

    10

    Team

    BL

    Brad Lightcap

    COO, OpenAI

    Jeff Lawson

    Jeff Lawson

    JW

    Jon Wang

    SG

    Serena Ge

    YY

    Yoland Yan

    Zach Perret

    Zach Perret

    EK

    Ethan Kurzweil

    Managing Partner

    Portfolio Breakdown

    Stage Distribution

    Sector Distribution

    Investment Activity

    DealsAvg Round Size

    Portfolio

    31 investments
    CompanyRoundAmountDate
    FFathom TherapeuticsSeries A$47MApr 2026
    YYuzu HealthSeries A$35MApr 2026
    Yuzu Health logoYuzu HealthSeries A$35MApr 2026
    Didero logoDideroSeries A$30MFeb 2026
    Didero logoDideroSeries A$30MFeb 2026
    Decagon logoDecagonSeries D—Jan 2026
    Comfy logoComfySeries A$30MJan 2026
    Yuzu Health logoYuzu HealthSeries A$35MJan 2026
    Didero logoDideroSeries A$30MJan 2026
    ComfyUI logoComfyUISeries A$19MJan 2026
    Comfy logoComfyGrowth$30MJan 2026
    Assort Health logoAssort HealthSeries C—Jan 2026
    Serval logoServalSeries A$47MOct 2025
    Serval logoServalSeries A$47MOct 2025
    Datacurve logoDatacurveSeries A$15MOct 2025
    Assort Health logoAssort HealthSeries B$76MSep 2025
    Persona logoPersonaSeries D$200MApr 2025
    Persona logoPersonaSeries D$200MApr 2025
    Assort Health logoAssort HealthSeries A$22MApr 2025
    Persona logoPersonaSeries D$200MJan 2025
    Assort Health logoAssort HealthSeries B$76MJan 2025
    Assort Health logoAssort HealthSeries A$22MJan 2025
    ComfyUI logoComfyUISeries A$19MJan 2024
    Comfy logoComfySeries A$19MJan 2024
    Meticulous logoMeticulousSeries A$15M—
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    Top Co-Investors

    GG16 shared
    Neo4 shared
    Rough Draft4 shared
    M123 shared
    Headline3 shared
    A*3 shared
    Felicis3 shared
    Accel3 shared
    BOND3 shared

    Last updated: 27 September 2026