Cleveland Clinic is a nonprofit academic medical center founded in 1921 in Cleveland, Ohio, that invests in healthcare and life-sciences startups through its corporate venture arm, Cleveland Clinic Ventures. The arm spins out and backs companies based on Cleveland Clinic intellectual property, having launched over 80 spinoff companies since 2000.
75% of their portfolio is in Healthcare. Deal activity decreased year-over-year (2 deals in the last 12 months vs 3 prior). Average disclosed round size is $26.9M (across 26 rounds with reported amounts).
Portfolio
16
Fund Size
—
Top Stage
Series A
Last 12 Mo
2
Team
Todd Schwarzinger
Partner Digital Health & Medical Devices
Daniel Lee, JD, LLM
Senior Director
Giedre Ruzgaite, PhD, CLP
Associate Director Digital Health & Therapeutics
JD Friedland, MBA
Executive Director
Jerry Wilmink, PhD, MBA
Director Digital Health
Joseph Rich, JD, MBA
Executive Director Innovations Operations
Partha Paul, PhD, MBA
Director Medical Devices
Saqib Sachani, PhD, MBA
Director
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
Portfolio
| Company | Round | Amount | Date |
|---|---|---|---|
 Enspire DBS Therapy | Series B | $10.3M | Jan 2026 |
 Mediview XR | Series A | $24M | Oct 2025 |
 Strolll | Series A | — | Mar 2025 |
 Xealth | Ipo | $50M | Jan 2025 |
 Xealth | Ipo | $50M | Jan 2025 |
 1m | Series A | $10M | Dec 2024 |
 Dyania Health | Series A | $10M | Oct 2024 |
 XII Medical | Series B | $45M | Aug 2024 |
 NeuroTherapia | Series B | $12.3M | Aug 2024 |
| Dyania Health | Series A | $10M | Jan 2024 |
| NeuroTherapia | Series B | $12.3M | Jan 2024 |
| Enspire DBS Therapy | Series B | $17.6M | Aug 2023 |
| Mediview XR | Series A | $15M | May 2023 |
| Mediview XR | Strategic | $15M | May 2023 |
| Mediview XR | Unknown | $15M | Jan 2023 |
| CCenterline Biomedical Inc | Series B | $33M | Jun 2022 |
| XII Medical | Series A | $30M | May 2022 |
 Avaneer Health | Seed | $50M | Jan 2022 |
| Xealth | Series B | $24M | Sep 2021 |
| Xealth | Series B | $24M | Sep 2021 |
 Enable Injections | Series B | $50M | Oct 2018 |
| AAutonomic Technologies | Series D | $43.2M | Jan 2015 |
| CCastlight | Series C | $60M | Mar 2014 |
| AAutonomic Technologies | Series C | $32M | Oct 2011 |
| AAutonomic Technologies | Series C | $32M | Jan 2011 |
Top Co-Investors
Last updated: 20 October 2026