D. E. Shaw Ventures is the venture capital and growth equity investing arm of the D. E. Shaw group, partnering with founding teams from post-seed through growth stages. The firm leverages deep technical expertise, analytical rigor, and quantitative finance approaches to invest in transformative private enterprises across AI, fintech, enterprise software, and other technology sectors.
They made 5 investments in the last 12 months. Average disclosed round size is $192.2M (across 26 rounds with reported amounts).
Portfolio
21
Fund Size
—
Top Stage
Series C
Last 12 Mo
5
Team
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
33 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 ThreatLocker, Inc. | Series F | $190M | Jul 2026 |
 Baseten | Series B | $1.5B | Jun 2026 |
 Anthropic | Series H | — | May 2026 |
 Mytra | Series C | $120M | Jan 2026 |
| ThreatLocker, Inc. | Series F | $190M | Jan 2026 |
 AlphaSense | Series C | $350M | Jan 2026 |
| Anthropic | Series G | — | Jan 2026 |
| AAnthropic, PBC | Series H | — | Jan 2026 |
| AAnthropic, PBC | Series G | — | Jan 2026 |
 AlphaSense | Growth | $100M | Jan 2026 |
| EEleven Labs | Series D | — | Jan 2026 |
| Baseten | Series E | $300M | Jan 2026 |
 Neural Concept | Series C | $100M | Dec 2025 |
 Flox | Series B | $25M | Jan 2025 |
| Neural Concept | Series C | $100M | Jan 2025 |
 Ramp | Series D | $150M | Apr 2024 |
| Mytra | Series B | $50M | Jan 2024 |
| ThreatLocker, Inc. | Series D | $115M | Jan 2024 |
| Anthropic | Series H | $450M | Jan 2023 |
 Tasso | Series B | $100M | Dec 2021 |
 MaintainX | Series B | $39M | Jun 2021 |
| Tasso | Growth | — | Jan 2021 |
| Tasso | Growth | $6.1M | Mar 2019 |
| OOpenAI Group PBC | Unknown | $1B | Jan 2019 |
 QC Ware | Series A | $6.5M | Jul 2018 |
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Top Co-Investors
Greenoaks Capital7 shared
Altimeter Capital Management, LP7 shared
D1 Capital Partners6 shared
Coatue Management LLC6 shared
General Catalyst6 shared
Insight Partners6 shared
Blackstone Inc.5 shared
Baillie Gifford5 shared
Jane Street Capital5 shared
Lightspeed Venture Partners5 shared
MGX5 shared
Sequoia Capital5 shared
The Goldman Sachs Group, Inc.3 shared
Techstars3 shared
Foresite Capital3 shared
RA Capital Management3 shared
Addition3 shared
General Atlantic3 shared
CapitalG3 shared
Last updated: 27 September 2026