D. E. Shaw Ventures, the venture capital arm of D. E. Shaw & Co., focuses on emerging technologies and disruptive business models, particularly in sectors like fintech, software, deep-tech, biotechnology, artificial intelligence, renewable energy, and cybersecurity. Their strategy employs a rigorous, quantitative, and data-driven approach, seeking startups with distinct technological or mathematical advantages and leveraging their expertise in computational finance and proprietary algorithms.
40% of their portfolio is in AI. They made 2 investments in the last 12 months. Their most common stage is series-c (40% of deals). Average disclosed round size is $79.5M (across 5 rounds with reported amounts).
Portfolio
5
Fund Size
—
Top Stage
Series C
Last 12 Mo
2
Team
Anne Dinning
Managing Director, Chair of Executive Committee
Eddie Fishman
Venture Partner
Edwin Jager
Partner
Alexis Halaby
Member of Executive Committee
Anoop Prasad
Member of Executive Committee
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
Portfolio
| Company | Round | Amount | Date |
|---|---|---|---|
 Mytra | Series C | $120M | Jan 2026 |
 Neural Concept | Series C | $100M | Dec 2025 |
 QC Ware | Series A | $6.5M | Jul 2018 |
| TTapjoy | Series B | $21M | Jan 2011 |
 MaintainX | Series D | $150M | — |
Top Co-Investors
Last updated: 10 April 2026