Deerfield Management Company is a New York-based investment firm founded in 1994, dedicated to advancing healthcare through investment, intelligence, and philanthropy. It makes public and private investments across the healthcare and biotechnology industries and is considered one of the largest dedicated healthcare investment firms in the world.
39% of their portfolio is in Biotech & Life Sciences. Deal activity decreased year-over-year (5 deals in the last 12 months vs 14 prior). Average disclosed round size is $80.8M (across 194 rounds with reported amounts).
Portfolio
147
Fund Size
$600M
Top Stage
Series C
Last 12 Mo
5
Team
JF
Jim Flynn
Managing Partner
AD
Anne Daub
Partner
JL
Jonathan Leff
Partner
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
210 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 Terns Pharmaceuticals | Series C | $87M | May 2026 |
 Ray Therapeutics | Series B | $125M | Apr 2026 |
 Neomorph | Series B | $100M | Apr 2026 |
 SHINE | Growth | $240M | Feb 2026 |
 Regenxbio | Series C | $30M | Jan 2026 |
 SHINE Technologies | Unknown | $240M | Jan 2026 |
 myLaurel | Seed | — | Nov 2025 |
 Axon | Series A | $32M | Sep 2025 |
| AAxon Vascular | Series A | $32M | Sep 2025 |
| BBridgeBio Oncology Therapeutics | Unknown | $261M | Aug 2025 |
 Actio Biosciences | Series B | $66M | Jun 2025 |
| myLaurel | Series A | $12M | Jun 2025 |
| AAtlas Data Storage | Seed | $155M | May 2025 |
 Ascertain | Series A | $10M | Apr 2025 |
 Perceive Bio | Series A | $15M | Feb 2025 |
| NNema Health | Series A | $14.5M | Jan 2025 |
 Nema | Series A | $14.5M | Jan 2025 |
 Reprieve Cardiovascular | Series B | $61M | Jan 2025 |
 Pleno | Series A | $40M | Dec 2024 |
| Pleno | Series B | $25M | Dec 2024 |
 Lomond Therapeutics | Series B | $44M | Nov 2024 |
 Petfolk | Series C | $36M | Oct 2024 |
 Pairwise | Series C | $40M | Sep 2024 |
 iRhythm Technologies | Debt | $200M | Sep 2024 |
 SpectraWAVE | Series B | $50M | Sep 2024 |
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Top Co-Investors
RA Capital Management29 shared
OrbiMed26 shared
Wellington Management19 shared
GV18 shared
Alexandria Venture Investments15 shared
Perceptive Advisors13 shared
Fidelity Investments12 shared
Foresite Capital12 shared
Optum Ventures11 shared
Redmile Group11 shared
ARCH Venture Partners11 shared
Sofinnova Partners10 shared
Casdin Capital10 shared
Ally Bridge Group10 shared
New Enterprise Associates9 shared
Logos Capital9 shared
Rock Springs Capital9 shared
Cormorant Asset Management9 shared
Decheng Capital9 shared
Last updated: 20 October 2026