Deerfield Management Company is a New York-based investment firm founded in 1994, dedicated to advancing healthcare through investment, intelligence, and philanthropy. It makes public and private investments across the healthcare and biotechnology industries and is considered one of the largest dedicated healthcare investment firms in the world.
39% of their portfolio is in Biotech & Life Sciences. Deal activity decreased year-over-year (5 deals in the last 12 months vs 12 prior). Average disclosed round size is $83.6M (across 100 rounds with reported amounts).
Portfolio
95
Fund Size
$600M
Top Stage
Series B
Last 12 Mo
4
Team
JF
Jim Flynn
Managing Partner
AD
Anne Daub
Partner
JL
Jonathan Leff
Partner
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
107 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 Neomorph | Series B | $100M | Apr 2026 |
 SHINE | Growth | $240M | Feb 2026 |
 myLaurel | Unknown | — | Nov 2025 |
 Axon | Series A | $32M | Sep 2025 |
| BBridgeBio Oncology Therapeutics | Unknown | $261M | Aug 2025 |
| myLaurel | Series A | $12M | Jun 2025 |
| NNema Health | Series A | $14.5M | Jan 2025 |
 Nema | Series A | $14.5M | Jan 2025 |
 Reprieve Cardiovascular | Series B | $61M | Jan 2025 |
 Pleno | Series A | $40M | Dec 2024 |
| Pleno | Series B | $25M | Dec 2024 |
| LLomond Therapeutics | Series B | $44M | Nov 2024 |
 Petfolk | Series C | $36M | Oct 2024 |
 Pairwise | Series C | $40M | Sep 2024 |
 SpectraWAVE | Series B | $50M | Sep 2024 |
 Elion Therapeutics | Series B | $81M | Jun 2024 |
 R3 Vascular | Series B | $87M | May 2024 |
| BBridgeBio Oncology Therapeutics (BBOT) | Growth | $200M | May 2024 |
 Lumeris | Growth | $100M | Apr 2024 |
 Cohere Health | Series C | $50M | Feb 2024 |
| Reprieve Cardiovascular | Series A | $42M | Jan 2024 |
 Adela | Series B | $48M | Sep 2023 |
 Bitterroot Bio | Series A | $145M | Jun 2023 |
 Ray Therapeutics | Series A | $100M | May 2023 |
| AAscend Gene & Cell Therapies | Series A | $132.5M | May 2023 |
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Top Co-Investors
RA Capital Management14 shared
OrbiMed13 shared
GV9 shared
Optum Ventures8 shared
Perceptive Advisors8 shared
Wellington Management7 shared
Longitude Capital6 shared
Abingworth LLP6 shared
ARCH Venture Partners6 shared
Foresite Capital6 shared
New Enterprise Associates5 shared
Flare Capital Partners5 shared
Sofinnova Partners5 shared
Polaris Partners5 shared
The Invus Group, LLC5 shared
Qiming Venture Partners USA5 shared
Alexandria Venture Investments5 shared
SR One5 shared
Novo Holdings A/S5 shared
Versant Ventures4 shared
Last updated: 7 September 2026