Optum Ventures is an independent venture capital firm founded in 2017 in partnership with UnitedHealth Group, investing in companies at the intersection of technology and healthcare. With over $2 billion in assets under management across 6 funds, OV backs stage-agnostic healthcare innovation from early-stage to growth equity.
66% of their portfolio is in Healthcare. Deal activity increased 80% year-over-year (9 deals in the last 12 months). Average disclosed round size is $61.2M (across 109 rounds with reported amounts).
Portfolio
74
Fund Size
—
Top Stage
Series A
Last 12 Mo
9
Team
Larry Renfro
Managing Partner
Laura Veroneau
Managing Partner
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
115 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 Greater Good Health | Debt | $20.5M | Mar 2026 |
 Chamber Cardio | Series A | $60M | Feb 2026 |
 Gyde | Series C | $60M | Jan 2026 |
 Risa | Series A | — | Jan 2026 |
| RRisa Labs | Series A | $11.1M | Jan 2026 |
 Bunkerhill Health | Seed | $55M | Jan 2026 |
| Gyde | Seed | $60M | Jan 2026 |
 Reema Health | Series B | $19M | Dec 2025 |
 CoPlane | Seed | $14M | Nov 2025 |
 Imagine Pediatrics | Series B | $67M | Sep 2025 |
 Imagine Pediatrics | Series B | $67M | Sep 2025 |
 Ambience | Series C | — | Jul 2025 |
 Ambience | Series C | $243M | Jul 2025 |
 Ambience Healthcare, Inc. | Series C | $243M | Jul 2025 |
| NNema Health | Series A | $14.5M | Jan 2025 |
 Nema | Series A | $14.5M | Jan 2025 |
 Adaptive | Series A | $50M | Jan 2025 |
| Ambience Healthcare, Inc. | Series C | $243M | Jan 2025 |
| Ambience | Series C | $243M | Jan 2025 |
| Imagine Pediatrics | Unknown | $67M | Jan 2025 |
| Imagine Pediatrics | Unknown | $67M | Jan 2025 |
 Synapticure | Series A | $25M | Nov 2024 |
 CareSyntax | Series C | $180M | Aug 2024 |
 Humata Health | Unknown | $25M | Jun 2024 |
| Ambience | Series B | $70M | Feb 2024 |
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Top Co-Investors
Oak HC/FT19 shared
.406 Ventures15 shared
Kleiner Perkins12 shared
Deerfield12 shared
Andreessen Horowitz11 shared
Symphony Ventures10 shared
Sound Ventures9 shared
Heartcore Capital8 shared
Balderton Capital8 shared
OpenAI Startup Fund7 shared
General Catalyst7 shared
Frist Cressey Ventures7 shared
BoxGroup7 shared
Primary Venture Partners7 shared
LRVHealth7 shared
RA Capital Management7 shared
Tusk Venture Partners6 shared
Insight Partners6 shared
First Round Capital6 shared
Longitude Capital6 shared
Last updated: 7 October 2026