Optum Ventures is a venture capital firm focused on transforming healthcare by investing in innovative digital health companies, particularly early to growth-stage startups that leverage data-driven technologies to enhance healthcare delivery, access, and payment systems. Their strategy involves providing capital, along with Optum's extensive healthcare expertise and market presence, to accelerate the growth and market adoption of their portfolio companies' solutions.
83% of their portfolio is in Healthcare. Deal activity increased 300% year-over-year (4 deals in the last 12 months). Average disclosed round size is $66.1M (across 46 rounds with reported amounts).
Portfolio
46
Fund Size
$2B
Top Stage
Series B
Last 12 Mo
4
Team
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
46 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 Chamber Cardio | Series A | $60M | Feb 2026 |
| GGyde | Series C | $60M | Jan 2026 |
| RRISA Labs | Series A | $11.1M | Jan 2026 |
 Ambience Healthcare | Series C | $243M | Jul 2025 |
| NNema Health | Series A | $14.5M | Jan 2025 |
| Ambience Healthcare | Series B | $70M | Feb 2024 |
 Cortica, Inc. | Growth | $75M | Apr 2023 |
| BBehaVR | Series B | $13M | Dec 2022 |
 DispatchHealth | Growth | $259M | Nov 2022 |
 Alma | Series D | $130M | Aug 2022 |
 Digital Diagnostics | Series B | $75M | Aug 2022 |
 Greater Good Health | Seed | $10M | May 2022 |
 Loop | Series B | $25M | Apr 2022 |
 Brightline | Series C | $105M | Mar 2022 |
 Vira Health | Series A | $12M | Mar 2022 |
| SSomatus | Series E | $325M | Feb 2022 |
 Secureframe | Series B | $56M | Feb 2022 |
 Equip | Series B | $58M | Feb 2022 |
 Future | Series C | $75M | Feb 2022 |
 Garner Health | Series B | $45M | Dec 2021 |
| Alma | Series C | $50M | Aug 2021 |
 Ultromics | Series B | $33M | Aug 2021 |
 Rey | Series A | $10M | Jul 2021 |
| Brightline | Series B | $72M | Jun 2021 |
 Kaia Health | Series C | $75M | Apr 2021 |
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Top Co-Investors
Oak HC/FT7 shared
General Catalyst4 shared
.406 Ventures4 shared
Kleiner Perkins4 shared
Humana3 shared
Deerfield3 shared
F-Prime Capital3 shared
Sound Ventures3 shared
Longitude Capital3 shared
Symphony Ventures3 shared
GV (Google Ventures)3 shared
Blue Venture Fund3 shared
Deerfield Management Company3 shared
HLM Venture Partners2 shared
Transformation Capital2 shared
Andreessen Horowitz2 shared
OpenAI Startup Fund2 shared
Tusk Ventures2 shared
TI Platform2 shared
Oxford Sciences Innovation2 shared
Last updated: 15 April 2026