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    Main Sequence

    Sydney, AustraliaFounded 2017

    Main Sequence is a venture capital firm that focuses on investing in deep technology companies translating Australian research into global businesses, aiming to solve major global challenges like decarbonization and feeding a growing population. Their strategy involves early-stage investments (seed to Series B) and a "venture science" model, actively partnering with researchers and universities to build companies from scientific discoveries.

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    Portfolio

    11

    Fund Size

    $1B

    Top Stage

    Series B

    Last 12 Mo

    2

    Stage Distribution

    Portfolio

    11 investments
    CompanyRoundAmountDate
    UluuSeries A$16MOct 2025
    Morse MicroSeries C$59MSep 2025
    JDoodleSeed$2.2MJun 2023
    EnduaSeries A$7.8MMay 2023
    UluuSeed$5.3MNov 2022
    LumachainSeries A$19.5MAug 2022
    Q-CTRLSeries B$25MNov 2021
    v2FoodSeries B$45MAug 2021
    BarajaSeries B$31MMar 2021
    EmesentSeed$2.5MNov 2018
    Gilmour SpaceSeries B$36M

    Top Co-Investors

    Blackbird3 shared
    Hostplus2 shared
    Sierra Ventures1 shared
    DCVC1 shared
    In-Q-Tel1 shared
    Burda Principal Investments1 shared
    Startmate1 shared
    Queensland Investment Corporation1 shared
    Astanor1 shared
    HESTA1 shared
    Regal1 shared

    Last updated: 3 March 2026