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Main Sequence is an Australian deep-tech venture capital firm founded by CSIRO in 2017 to bridge the valley of death in research commercialisation. It employs a 'Venture Science' model, pairing scientific discoveries with industry expertise and capital to build companies across space, decarbonisation, AI, food security, healthcare, and industrial productivity.
Deal activity increased 267% year-over-year (11 deals in the last 12 months). Average disclosed round size is $32.6M (across 66 rounds with reported amounts).
Portfolio
54
Fund Size
$300M
Top Stage
Series A
Last 12 Mo
11
Team
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
81 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 Emesent | Series A | $25M | Jul 2026 |
 DeteQT | Seed | — | Apr 2026 |
 Advanced Navigation | Series C | $102.7M | Mar 2026 |
 Breaker | Seed | $6M | Feb 2026 |
 Kasada | Series B | $20M | Feb 2026 |
| GGilmour Space Technologies | Series E | $217M | Jan 2026 |
 Eden Brew | Series A | $24.5M | Jan 2026 |
 Diraq | Series A | $100M | Jan 2026 |
 The EVERY Company | Series D | $55M | Nov 2025 |
 Clara Foods | Series D | — | Nov 2025 |
 every, Inc. | Series D | $55M | Nov 2025 |
 ULUU | Series A | $16M | Oct 2025 |
 Morse Micro | Series C | $59M | Sep 2025 |
 Levur | Pre-Seed | $1.2M | May 2025 |
 ElectraLith | Series A | $27.5M | Jan 2025 |
 Quantum Brilliance | Series A | $20M | Jan 2025 |
| QQuantum Diamonds | Series A | $20M | Jan 2025 |
| Levur | Pre-Seed | $1.2M | Jan 2025 |
| The EVERY Company | Series A | $22.5M | Sep 2024 |
| GGilmour Space Technologies | Series D | $55M | Feb 2024 |
 Cauldron | Unknown | $13.3M | Jan 2024 |
 Avarni | Seed | — | Nov 2023 |
 Skykraft | Unknown | $100M | Oct 2023 |
 JDoodle | Seed | — | Jun 2023 |
 Endua | Seed | — | May 2023 |
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Top Co-Investors
Horizons Ventures14 shared
In-Q-Tel11 shared
Blackbird10 shared
Hostplus9 shared
Clean Energy Finance Corporation8 shared
Startmate7 shared
SOSV6 shared
New Agrarian4 shared
McWin Capital Partners4 shared
HongShan4 shared
Skip Capital4 shared
TenEleven Ventures4 shared
Artesian4 shared
Grok Ventures4 shared
Investible4 shared
B373 shared
Hitachi Ventures3 shared
Wollemi Capital3 shared
Right Click Capital3 shared
Last updated: 7 October 2026