New Leaf Venture Partners is a venture capital firm focused exclusively on healthcare technology, investing across biopharmaceuticals, medical devices, molecular diagnostics, and healthcare IT. Founded in 2005 as a healthcare spinoff from the Sprout Group, the firm partners with companies from early-stage through public offerings.
Deal activity increased 300% year-over-year (4 deals in the last 12 months). Average disclosed round size is $52.2M (across 58 rounds with reported amounts).
Portfolio
52
Fund Size
—
Top Stage
Series C
Last 12 Mo
3
Team
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
59 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 BrightInsight | Unknown | $13M | Jan 2026 |
 Electra | Series C | $183M | Oct 2025 |
| EElectra Therapeutics | Series C | $183M | Oct 2025 |
 Celera | Series A | $20M | Aug 2025 |
| AAbcuro, Inc. | Series C | $200M | Feb 2025 |
 Star Therapeutics | Series D | $125M | Jan 2025 |
 Neurava | Seed | $2.3M | Apr 2024 |
 Flosonics Medical | Series C | $20M | Mar 2024 |
 Deciphera Pharmaceuticals | Series C | $52M | Jan 2023 |
 Arine | Series B | $29M | Aug 2022 |
| EElectra Therapeutics | Series B | $84M | Feb 2022 |
| CCleerly Coronary | Series B | $43M | Jun 2021 |
 Akili Interactive Labs, Inc. | Series D | $110M | May 2021 |
| AAkili, Inc. | Series D | $110.0M | May 2021 |
| AAkili, Inc. | Series D | $110M | Jan 2021 |
 Edgewise Therapeutics | Series B | $50M | Sep 2019 |
 Renovacor | Series A | $11M | Jan 2019 |
| RRenovacor | Series A | $11M | Jan 2019 |
| RRenovacor | Series A | $11M | Jan 2019 |
 ReViral | Series C | $44M | Aug 2018 |
 Rallybio | Series A | $37M | Apr 2018 |
 Arvinas | Series C | $55M | Apr 2018 |
| CCurasen | Series A | $54.5M | Jan 2018 |
| AAptinyx Inc | Series B | $70M | Dec 2017 |
 Kit Check | Series C | $15M | Jun 2016 |
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Top Co-Investors
OrbiMed17 shared
Redmile Group8 shared
RA Capital Management7 shared
Canaan Partners6 shared
Frazier Healthcare Partners6 shared
Sanofi Ventures5 shared
Foresite Capital5 shared
Morgenthaler Ventures5 shared
Cormorant Asset Management4 shared
Longitude Capital4 shared
Osage University Partners4 shared
Blue Owl Capital3 shared
HBM Healthcare Investments3 shared
Deerfield3 shared
Agent Capital3 shared
Soleus Capital3 shared
Adams Street Partners3 shared
Venrock3 shared
New Enterprise Associates3 shared
Alta Partners3 shared
Last updated: 9 September 2026