OS Fund is a venture capital fund founded by Bryan Johnson in 2014 that invests in entrepreneurs, inventors, and scientists using applied intelligence to commercialize breakthrough discoveries in genomics, synthetic biology, diagnostics, and advanced materials. The firm aims to back platform-level science innovations that 'rewrite the operating systems of life.'
89% of their portfolio is in Biotech & Life Sciences. Average disclosed round size is $32.0M (across 16 rounds with reported amounts).
Portfolio
10
Fund Size
$100M
Top Stage
Series A
Last 12 Mo
0
Team
JK
Jeff Klunzinger
Managing Director
BJ
Bryan Johnson
Founder
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
18 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 Arzeda | Series B | $33M | Mar 2022 |
 Emulate | Series E | $82M | Sep 2021 |
 Synthego | Series C | $110M | Oct 2018 |
 Verge Genomics | Series A | — | Jul 2018 |
| Arzeda | Series A | $12M | Jul 2017 |
| Synthego | Series B | — | Jan 2017 |
 Lygos | Series A | $13M | Dec 2016 |
 3Scan | Series B | $14M | Jul 2016 |
| Emulate | Series B | $45M | Jan 2016 |
| Lygos | Series A | $13M | Jan 2016 |
 Ginkgo Bioworks | Series B | $45M | Jul 2015 |
| Ginkgo Bioworks | Series A | $9M | Mar 2015 |
| Ginkgo Bioworks | Series A | $9M | Jan 2015 |
| Ginkgo Bioworks | Series B | $45M | Jan 2015 |
 A-Alpha Bio | Seed | $22.4M | — |
 NuMat | Unknown | $12.4M | — |
 Verge | Series A | $32M | — |
| Lygos | Series B | $15.5M | — |
Top Co-Investors
Y Combinator8 shared
Founders Fund4 shared
Felicis3 shared
First Round Capital3 shared
DCVC2 shared
8VC2 shared
Menlo Ventures2 shared
AME Cloud Ventures2 shared
Casdin Capital2 shared
British International Investment2 shared
Washington Research Foundation2 shared
Bioeconomy Capital2 shared
Agent Capital2 shared
ALS Investment Fund2 shared
Fifty Years2 shared
Breakout Ventures2 shared
Perceptive Advisors2 shared
Labcorp2 shared
+ND Capital2 shared
Last updated: 20 October 2026