Breakout Ventures is a San Francisco-based venture capital firm that invests in science-driven companies across technology, biology, and chemistry sectors. The firm partners with exceptional founders scaling scientific innovation to build the breakout companies of the future.
40% of their portfolio is in Biotech & Life Sciences. Their most common stage is seed (40% of deals). Average disclosed round size is $24.5M (across 24 rounds with reported amounts).
Portfolio
24
Fund Size
$114M
Top Stage
Seed
Last 12 Mo
1
Team
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
25 investments
| Company | Round | Amount | Date |
|---|---|---|---|
| AAquaPoro | Seed | $5M | Jan 2026 |
 PHANTOM NEURO | Series A | $19M | Apr 2025 |
 ENPLUSONE BIO | Seed | $10M | Feb 2025 |
 Cytovale | Series D | $100M | Oct 2024 |
 ShiraTronics, Inc | Series A | $3M | Jan 2023 |
| PHANTOM NEURO | Seed | $6M | Oct 2022 |
| SStadium Live Studios, Inc. | Series A | $10M | Jul 2022 |
 Beam Dental | Series E | $80M | Mar 2021 |
 Beam Benefits | Series E | $80M | Mar 2021 |
 IMMUSOFT | Series B | $20M | Jan 2019 |
 Summersalt | Series A | $6M | Oct 2018 |
| OOars + Alps | Seed | $1.3M | Jun 2017 |
| 33scan | Series B | $14M | Jul 2016 |
 Modern Meadow | Series B | $40M | Jun 2016 |
 Interior Define | Unknown | — | — |
 A-Alpha Bio | Seed | $22.4M | — |
 Cortexyme | Series A | $15M | — |
 Phylagen | Series A | $14M | — |
 PASSKEY THERAPEUTICS | Seed | $20M | — |
 SURF BIO | Seed | $16M | — |
 PassKey | Seed | $20M | — |
 Canaery | Seed | $4M | — |
 EnPlusOne Biosciences | Unknown | $10M | — |
| PParthenon Therapeutics | Series A | $65M | — |
 Copernic | Seed | $8M | — |
Top Co-Investors
Dolby Family Ventures4 shared
Alexandria Venture Investments4 shared
Northpond Ventures3 shared
Nationwide2 shared
Georgian Partners2 shared
Time BioVentures2 shared
Draper Associates2 shared
LionBird2 shared
Western Technology Investment2 shared
OS Fund2 shared
Perceptive Advisors2 shared
Pfizer Ventures2 shared
Innovation Endeavors2 shared
Wireframe Ventures2 shared
Collaborative Fund1 shared
Horizons Ventures1 shared
Red Swan Ventures1 shared
Iconiq Capital, LLC1 shared
Last updated: 8 September 2026