OSF HealthCare, through its corporate venture arm OSF Ventures, invests financially, operationally, and strategically in emerging healthcare technology companies to improve patient outcomes, enhance patient experience, and reduce the cost of care. It is an integrated health system founded by The Sisters of the Third Order of St. Francis, headquartered in Peoria, Illinois.
71% of their portfolio is in Healthcare. Deal activity decreased year-over-year (1 deals in the last 12 months vs 3 prior). Average disclosed round size is $24.2M (across 16 rounds with reported amounts).
Portfolio
16
Fund Size
$100M
Top Stage
Series B
Last 12 Mo
1
Team
SL
Stan Lynall
Vice President of Ventures Investments
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
17 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 Monteris Medical | Series E | $28M | Mar 2026 |
 410 Medical | Series B | $14M | Mar 2025 |
 PhotoniCare | Series B | $4.6M | Dec 2024 |
 Pieces | Growth | $25M | Sep 2024 |
 Socially Determined | Series B | $26M | Jan 2022 |
| DDotCom Therapy | Series A | $13M | Sep 2021 |
 Gauss | Series C | $30M | Jan 2020 |
 Health Scholars | Series B | $17M | Jan 2020 |
 InsightRX | Series A | $10M | Sep 2019 |
 Gauss Surgical | Series C | $20M | Oct 2018 |
| Gauss | Series C | $20M | Oct 2018 |
 Health Catalyst | Series E | $70M | Feb 2016 |
 TailorMed | Unknown | $40M | — |
 Exo Imaging | Growth | — | — |
 Current Health | Series B | $43M | — |
| AArray Behavioral Care | Unknown | $25M | — |
 PatientWisdom | Series A | $1M | — |
Top Co-Investors
Northwell Health3 shared
LRVHealth3 shared
Memorial Hermann Health System2 shared
Y Combinator2 shared
OCA Ventures2 shared
MultiCare Health System1 shared
Scale Venture Partners1 shared
Learn Capital1 shared
Kaiser Permanente Ventures1 shared
Leavitt Equity Partners1 shared
Sands Capital1 shared
UPMC Enterprises1 shared
Tenaya Capital1 shared
Norwest Venture Partners1 shared
Sequoia Capital1 shared
HV Capital1 shared
Polaris Innovation Fund1 shared
SBVA1 shared
Corewell Health Ventures1 shared
W Health Ventures1 shared
Last updated: 9 September 2026