OSF HealthCare, through its corporate venture arm OSF Ventures, invests financially, operationally, and strategically in emerging healthcare technology companies to improve patient outcomes, enhance patient experience, and reduce the cost of care. It is an integrated health system founded by The Sisters of the Third Order of St. Francis, headquartered in Peoria, Illinois.
59% of their portfolio is in Healthcare. Deal activity decreased year-over-year (1 deal in the last 12 months vs 2 prior). Average disclosed round size is $25.9M (across 26 rounds with reported amounts).
Portfolio
19
Fund Size
$100M
Top Stage
Series B
Last 12 Mo
1
Team
SL
Stan Lynall
Vice President of Ventures Investments
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
27 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 Monteris Medical | Series E | $28M | Mar 2026 |
 410 Medical | Unknown | $12M | Jan 2026 |
| 410 Medical | Series B | $14M | Mar 2025 |
 PhotoniCare | Series B | $4.6M | Dec 2024 |
 Pieces | Growth | $25M | Sep 2024 |
 Socially Determined | Series B | $26M | Jan 2022 |
| DDotCom Therapy | Series A | $13M | Sep 2021 |
 Inflammatix | Series D | $102M | Mar 2021 |
| DDotCom Therapy | Unknown | $13M | Jan 2021 |
 Health Scholars | Seed | $17M | Jan 2020 |
 Gauss | Series C | $30M | Jan 2020 |
| Health Scholars | Series B | $17M | Jan 2020 |
| PhotoniCare | Series A | $5.2M | Jan 2020 |
 InsightRx | Series A | $10M | Sep 2019 |
| InsightRx | Series A | $10M | Jan 2019 |
 Gauss Surgical | Series C | $20M | Oct 2018 |
| Gauss | Series C | $20M | Oct 2018 |
 Renovia | Series B | $32.3M | Aug 2018 |
| Renovia | Debt | $10M | Aug 2018 |
 PatientWisdom | Series A | $1M | Sep 2017 |
 Health Catalyst | Series E | $70M | Feb 2016 |
 TailorMed | Unknown | $40M | — |
 Exo Imaging | Growth | — | — |
 Current Health | Series B | $43M | — |
| AArray Behavioral Care | Series B | $25M | — |
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Top Co-Investors
LRVHealth4 shared
Northwell Health3 shared
Northpond Ventures3 shared
Perceptive Advisors3 shared
Memorial Hermann Health System2 shared
Providence Ventures2 shared
Rock Health2 shared
Leawood Venture Capital2 shared
Plug and Play Tech Center2 shared
Premier Partners2 shared
InnovaHealth Partners2 shared
Y Combinator2 shared
Sovereign's Capital2 shared
Capital Midwest Fund2 shared
Service Provider Capital2 shared
Longwood Fund2 shared
Ascension Ventures2 shared
Cormorant Asset Management2 shared
Western Technology Investment2 shared
OCA Ventures2 shared
Last updated: 20 October 2026