Pontifax is a healthcare-dedicated venture capital firm that invests in transformative, cutting-edge life sciences technologies at all development stages. The firm backs breakthrough innovation across therapeutic areas, both by establishing its own companies and by partnering with existing management teams to nurture startups to maturity.
46% of their portfolio is in Biotech & Life Sciences. Deal activity increased 75% year-over-year (7 deals in the last 12 months). Average disclosed round size is $71.6M (across 73 rounds with reported amounts).
Portfolio
49
Fund Size
—
Top Stage
Series B
Last 12 Mo
7
Team
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
89 investments
| Company | Round | Amount | Date |
|---|---|---|---|
| PPrecirix | Series B | — | Aug 2026 |
 Crystalys Therapeutics Inc | Series B | $130M | Jul 2026 |
 Adcendo ApS | Series C | $75M | Apr 2026 |
 Adcytherix | Series A | — | Oct 2025 |
 Step Pharma | Series C | — | Oct 2025 |
 Crystalys | Series A | $205M | Sep 2025 |
| Crystalys Therapeutics Inc | Series A | $205M | Sep 2025 |
 Abcuro, Inc. | Series C | $200M | Feb 2025 |
| LLutris Pharma | Unknown | $30M | Jan 2025 |
 Indapta Therapeutics | Unknown | $22.5M | Dec 2024 |
| Adcendo ApS | Series B | $135M | Nov 2024 |
| Adcytherix | Seed | — | Jun 2024 |
| Indapta Therapeutics | Unknown | $22.5M | Jan 2024 |
| Adcendo ApS | Series B | $135M | Jan 2024 |
| AAgomab | Series B | $100M | Oct 2023 |
 Amolyt Pharma | Series C | $130M | Jan 2023 |
 Amolyt Pharma | Series C | $138M | Jan 2023 |
| PPrecirix | Series B | — | Mar 2022 |
| Indapta Therapeutics | Series A | $60M | Jan 2022 |
| PPrecirix | Seed | — | Jan 2022 |
| EEmergence Therapeutics | Series A | — | Dec 2021 |
| AAntios Therapeutics, Inc. | Series B | $75M | Nov 2021 |
| AAntios Therapeutics, Inc. | Series A | $75M | Nov 2021 |
| Amolyt Pharma | Series B | $80M | Sep 2021 |
 Vanqua Bio | Series B | $85M | Sep 2021 |
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Top Co-Investors
OrbiMed31 shared
RA Capital Management25 shared
Novo Capital15 shared
Alexandria Venture Investments12 shared
Kurma Partners12 shared
Surveyor Capital11 shared
Novo Holdings A/S10 shared
Andera Partners10 shared
Soleus Capital9 shared
Mass General Brigham Ventures9 shared
Adage Capital Management8 shared
HealthCap8 shared
EQT Life Sciences8 shared
Foresite Capital8 shared
DSC Investment8 shared
Omega Funds8 shared
Bpifrance7 shared
Dawn Biopharma7 shared
Triventures7 shared
Jeito Capital7 shared
Last updated: 20 October 2026