Omega Funds is a global healthcare venture capital firm that creates and invests in life sciences companies targeting the world's most urgent medical needs, across therapeutic areas including oncology, immunology, rare diseases, and precision medicine. Founded in 2004 and headquartered in Boston, the firm invests from early venture rounds through public company financing.
40% of their portfolio is in Biotech & Life Sciences. Average disclosed round size is $92.8M (across 162 rounds with reported amounts).
Portfolio
133
Fund Size
$647M
Top Stage
Series B
Last 12 Mo
10
Team
BJ
Brent Jiang
Operations
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
190 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 Vaderis Therapeutics | Unknown | $152M | Oct 2026 |
 Vaderis Therapeutics | Series B | $152.5M | Aug 2026 |
 Windward Bio | Unknown | $165M | May 2026 |
 Windward | Unknown | $165M | May 2026 |
 Alveus Therapeutics Inc | Series A | $37M | Feb 2026 |
 Third Arc Bio | Series A | $52M | Feb 2026 |
| Alveus Therapeutics Inc | Series A | $160M | Jan 2026 |
 Spiro Medical | Series A | $67M | Jan 2026 |
 Aviceda | Series C | — | Jan 2026 |
 Caldera Therapeutics | Series A | $75M | Jan 2026 |
 ImageneBio, Inc. | Unknown | $30M | Jan 2026 |
| AAviceda Therapeutics | Unknown | $207.5M | Jan 2026 |
 Protego | Series B | $130M | Dec 2025 |
| PProtego Biopharma | Series B | $130M | Dec 2025 |
 Artios | Series D | $115M | Nov 2025 |
 NRG Therapeutics | Series B | $50M | Sep 2025 |
| BBridgeBio Oncology Therapeutics | Unknown | $261M | Aug 2025 |
 Artbio | Series B | $132M | Jul 2025 |
 Ousia Pharma | Unknown | — | May 2025 |
| EEvolytes | Seed | — | Apr 2025 |
 Callio Therapeutics | Series A | $187M | Mar 2025 |
| Windward Bio | Series A | $200M | Jan 2025 |
| AAviceda Therapeutics | Series C | — | Jan 2025 |
| BBridgeBio Oncology Therapeutics | Unknown | $260M | Jan 2025 |
| PProtego Biopharma | Series B | $130M | Jan 2025 |
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Top Co-Investors
OrbiMed28 shared
RA Capital Management23 shared
Cormorant Asset Management22 shared
Surveyor Capital19 shared
Longitude Capital18 shared
Polaris Partners18 shared
Sofinnova Partners17 shared
Redmile Group17 shared
The Invus Group, LLC15 shared
Frazier Healthcare Partners15 shared
Casdin Capital14 shared
Atlas Venture14 shared
Alexandria Venture Investments14 shared
GV14 shared
Andera Partners14 shared
Foresite Capital13 shared
Wellington Management13 shared
Pfizer Ventures13 shared
Perceptive Advisors13 shared
F-Prime Capital12 shared
Last updated: 20 October 2026