
Samsara BioCapital is a venture capital firm founded in 2016 and based in Palo Alto, California. The firm partners with scientists and entrepreneurs to translate cutting-edge science into transformative medicines for patients, investing in innovative therapeutics across the biotech and life sciences sectors.
57% of their portfolio is in Biotech & Life Sciences. Their most common stage is series-b (43% of deals). Average disclosed round size is $99.0M (across 90 rounds with reported amounts).
Portfolio
84
Fund Size
$310.1M
Top Stage
Series B
Last 12 Mo
11
Team
Srini Akkaraju, MD, PhD
Founder & Managing Partner
Dan Spiegelman
Venture Partner
David Parry, PhD
Venture Partner
Eric Dobmeier, JD
Venture Partner
Guna Rajagopal, PhD
Venture Partner
Jim P. Edwards, PhD
Venture Partner
Keith Gottesdiener, MD
Venture Partner
Marcos Milla, PhD
Venture Partner
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
Portfolio
| Company | Round | Amount | Date |
|---|---|---|---|
| Series B | $100M | Mar 2026 | |
| PPrimmune Therapeutics Inc | Series B | $8.6M | Jan 2026 |
| Series B | $107M | Jan 2026 | |
| SSidewinder Therapeutics | Series B | $137M | Jan 2026 |
| Series B | $137M | Jan 2026 | |
| Series A | $93M | Jan 2026 | |
| CClaris Bio | Series B | — | Jan 2026 |
| Series B | $120M | Jan 2026 | |
| Series A | $47.5M | Dec 2025 | |
| Series A | $60M | Dec 2025 | |
| Series A | $70M | Oct 2025 | |
| Series D | $75M | Jun 2025 | |
| Series B | $52M | May 2025 | |
| Series D | $175M | Mar 2025 | |
| AAbcuro, Inc. | Series C | $200M | Feb 2025 |
| Series C | $112.3M | Oct 2024 | |
| EElektrofi | Series C | $112.3M | Oct 2024 |
| Series C | $175M | Oct 2024 | |
| Unknown | $410M | Oct 2024 | |
| Series B | $105M | Aug 2024 | |
| LLeap Therapeutics | Series B | $40M | Apr 2024 |
| Series C | $259M | Mar 2024 | |
| Series B | $67M | Jan 2024 | |
| Series A | $68.5M | Jan 2024 | |
| Series A | $60M | Nov 2023 |
Top Co-Investors
Last updated: 7 September 2026