SemperVirens Venture Capital
San Mateo, California, United StatesFounded 2018
SemperVirens Venture Capital is an ecosystem-driven venture capital firm that helps early-stage B2B startups transform complex industries across healthcare, financial technology, and workforce technology. The firm leverages a network of Fortune 500 executives and corporate venture partners to support founders with go-to-market strategies and customer sourcing.
38% of their portfolio is in Healthcare. Deal activity decreased year-over-year (4 deals in the last 12 months vs 6 prior). Their most common stage is series-a (45% of deals). Average disclosed round size is $38.9M (across 54 rounds with reported amounts).
Portfolio
44
Fund Size
$177M
Top Stage
Series A
Last 12 Mo
4
Team
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
60 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 UpSmith | Series A | — | Oct 2026 |
 Kubera Health | Seed | $6.5M | May 2026 |
 Midi | Series D | $100M | Feb 2026 |
 Midi Health | Series D | $100M | Feb 2026 |
| Kubera Health | Seed | $6.5M | Jan 2026 |
 Andel | Seed | $4.5M | Oct 2025 |
 Penguin AI | Series A | $29.7M | Sep 2025 |
 Certify | Series B | $40M | Jun 2025 |
 Salsa | Series A | — | Apr 2025 |
 Thatch | Series B | $40M | Apr 2025 |
 Delfina | Series A | $17M | Jan 2025 |
| DDelfina Care | Series A | — | Jan 2025 |
 Empathy | Series C | $72M | Jan 2025 |
| Certify | Series B | $40M | Jan 2025 |
 XP Health | Series B | $33.2M | Sep 2024 |
| Thatch | Series A | $38M | Sep 2024 |
 TechWolf | Series B | $42.8M | Jun 2024 |
| Midi | Series B | — | Apr 2024 |
 Take2 Ai | Seed | $14M | Apr 2024 |
| Midi Health | Series B | $60M | Jan 2024 |
| TTake2 | Seed | $3M | Jan 2024 |
| Midi | Series A | $25M | Sep 2023 |
| Midi Health | Series A | $25M | Sep 2023 |
 Cylinder | Series B | $31M | Sep 2023 |
 Laguna Health | Series A | $15M | May 2023 |
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Top Co-Investors
Index Ventures9 shared
General Catalyst9 shared
Felicis8 shared
GV7 shared
Andreessen Horowitz7 shared
Human Ventures6 shared
Y Combinator5 shared
Operator Collective5 shared
Icon Ventures5 shared
Emerson Collective5 shared
The General Partnership5 shared
Plug and Play Tech Center5 shared
Upfront Ventures5 shared
Company Ventures5 shared
Able Partners4 shared
Greycroft4 shared
Goodwater Capital4 shared
Reach Capital4 shared
Tiger Global Management, LLC3 shared
GingerBread Capital3 shared
Last updated: 20 October 2026