SignalFire is a venture capital firm that focuses on early-stage investments, from pre-seed to Series B, in sectors such as AI/ML, developer tools, B2B SaaS, healthcare, cybersecurity, and consumer industries. Their strategy is distinguished by an AI-native approach, leveraging their proprietary Beacon AI platform to source deals, identify promising startups, and provide extensive operational support to their portfolio companies.
Deal activity increased 120% year-over-year (11 deals in the last 12 months). Average disclosed round size is $42.8M (across 72 rounds with reported amounts).
Portfolio
75
Fund Size
$3B
Top Stage
Series A
Last 12 Mo
11
Team
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
75 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 VITL | Series A | $7.5M | Mar 2026 |
| QQualified Health | Series A | — | Mar 2026 |
| MMEGA | Series A | $11.5M | Mar 2026 |
 Grow Therapy | Series D | $150M | Mar 2026 |
 Solace Health | Series C | $130M | Feb 2026 |
| PPrudentia Sciences | Series A | $20M | Jan 2026 |
| RRuli.ai | Seed | $6M | Nov 2025 |
 EvenUp | Series E | $150M | Oct 2025 |
 Motion | Series C | $38M | Sep 2025 |
 SuperDial | Series A | $15M | Jun 2025 |
 Flock Freight | Series E | $60M | May 2025 |
 Wellth | Series C | $36M | Mar 2025 |
 Bicycle Health | Series B | $16.5M | Jan 2025 |
| EvenUp | Series D | $135M | Oct 2024 |
 PayZen | Series B | $32M | Aug 2024 |
 Unify | Seed | $8M | May 2024 |
| Grow Therapy | Series C | $88M | Apr 2024 |
 Lago | Series A | $15M | Mar 2024 |
 Tofu | Seed | $5M | Oct 2023 |
 Prophecy | Series B | $35M | Oct 2023 |
 Induced AI | Seed | $2.3M | Oct 2023 |
 Stampli | Series D | $61M | Oct 2023 |
 Kolena | Series A | $15M | Sep 2023 |
| HHorizon3 | Series C | $40M | Aug 2023 |
 Karat | Series B | $70M | Jul 2023 |
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Top Co-Investors
General Catalyst6 shared
FirstMark Capital6 shared
Y Combinator6 shared
NEA (New Enterprise Associates)5 shared
Insight Partners4 shared
BoxGroup4 shared
Felicis Ventures4 shared
Andreessen Horowitz3 shared
Initialized Capital3 shared
Founders Fund3 shared
Accel3 shared
Team83 shared
Bloomberg Beta3 shared
GLP3 shared
Menlo Ventures2 shared
Torch Capital2 shared
Tusk Ventures2 shared
Anthemis2 shared
Sequoia Capital2 shared
Transformation Capital2 shared
Last updated: 10 April 2026