AIData & AnalyticsEnterprise SoftwareFintechRobotics & AutomationHealthcareBiotech & Life SciencesCybersecurity
Two Sigma Ventures is an early-stage venture capital firm based in New York City, originating from the quantitative hedge fund Two Sigma Investments. It invests in technical founders leveraging data, computation, and AI across sectors like enterprise software, fintech, robotics, and healthcare. In 2025, the team spun out as an independent firm named Deviation Capital.
Average disclosed round size is $45.0M (across 114 rounds with reported amounts).
Portfolio
95
Fund Size
$300M
Top Stage
Series A
Last 12 Mo
1
Team
DP
Dusan Perovic
Partner
FS
Frances Schwiep
Partner
MJ
Matt Jacobus
Venture Partner
SC
Sidney Costabile
Partner
X(
Xinyi (Lucy) Ke
Vice President
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
121 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 FreeforM | Series B | $67M | Feb 2026 |
 Bedrock Robotics | Series C | $80M | Jul 2025 |
| NNetBox | Series B | — | Jul 2025 |
 Cerby | Series B | $40M | May 2025 |
 steadily | Series C | $30M | Apr 2025 |
 Tive | Series C | $40M | Jan 2025 |
 Arda Therapeutics | Series A | $43M | Oct 2024 |
 Distributional | Series A | $19M | Oct 2024 |
 Crossover Markets | Series A | $12M | Jun 2024 |
 Indico | Unknown | $19M | Jun 2024 |
 Gameto | Series C | $33M | May 2024 |
 Cosmos Innovation | Series A | $19.7M | Oct 2023 |
 Objective | Unknown | $13M | Oct 2023 |
 Membrane Labs | Series A | $20M | Oct 2023 |
| MMembrane Labs, Inc. | Series A | $20M | Oct 2023 |
| Cerby | Series A | $17M | Aug 2023 |
 Hyper Online | Seed | $3.6M | Jun 2023 |
 Netbox Labs | Series A | $20M | Apr 2023 |
| NNetBox | Series A | $20M | Apr 2023 |
| Crossover Markets | Seed | — | Mar 2023 |
 Hexagon Bio | Series B | $77.3M | Feb 2023 |
 Rive | Series A | $10M | Jan 2023 |
 Rive | Series A | $10M | Jan 2023 |
| CC3 Protocol | Seed | $6M | Jan 2023 |
 Cajal Neuroscience | Series A | $96M | Nov 2022 |
Page 1 of 5
Top Co-Investors
Felicis10 shared
Founder Collective9 shared
Madrona Venture Group8 shared
Scale Venture Partners7 shared
Khosla Ventures6 shared
Accel6 shared
Mubadala Ventures6 shared
Lux Capital6 shared
Digitalis Ventures6 shared
GV5 shared
Index Ventures5 shared
Salesforce Ventures5 shared
Obvious Ventures5 shared
RRE Ventures5 shared
Flow Traders5 shared
Alexandria Venture Investments5 shared
Heavybit5 shared
Alumni Ventures5 shared
Amplify Partners5 shared
Y Combinator4 shared
Last updated: 9 September 2026