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    UPMC Enterprises

    Pittsburgh, Pennsylvania, United StatesFounded 2014
    enterprises.upmc.comLinkedIn
    HealthcareBiotech & Life Sciences

    UPMC Enterprises is the innovation, commercialization, and venture capital arm of UPMC, a $28 billion health care provider and insurer based in Pittsburgh, PA. It invests in digital health solutions and translational sciences, including therapeutics, diagnostics, and medical devices, having committed $1 billion to life sciences investments.

    37% of their portfolio is in Healthcare. Deal activity decreased year-over-year (1 deal in the last 12 months vs 8 prior). Average disclosed round size is $49.6M (across 50 rounds with reported amounts).

    Find people at UPMC Enterprises on Goldilocks AI

    Portfolio

    45

    Fund Size

    $1B

    Top Stage

    Series B

    Last 12 Mo

    1

    Team

    David Okonkwo, MD, PhD

    David Okonkwo, MD, PhD

    Executive Vice President

    José-Alain Sahel, MD

    José-Alain Sahel, MD

    Executive Vice President

    Matthias Kleinz, DVM, PhD

    Matthias Kleinz, DVM, PhD

    Executive Vice President, UPMC Enterprises

    Nicole Ansani, PharmD

    Nicole Ansani, PharmD

    Senior Vice President, New Development Initiatives

    MJ

    Maryam Jalal, MS

    Senior Associate, Transaction Services

    Portfolio Breakdown

    Stage Distribution

    Sector Distribution

    Investment Activity

    DealsAvg Round Size

    Portfolio

    63 investments
    CompanyRoundAmountDate
    Moxe logoMoxeUnknown$25MOct 2026
    Precede Bio logoPrecede BioSeries B$63.5MJan 2026
    Penguin AI logoPenguin AISeries A$29.7MSep 2025
    Ultromics logoUltromicsSeries C$55MJul 2025
    Carta Healthcare logoCarta HealthcareSeries B$18.3MMay 2025
    Latigo Biotherapeutics logoLatigo BiotherapeuticsSeries B$150MMar 2025
    Ouro Medicines logoOuro MedicinesSeries A$120MJan 2025
    Raapid logoRaapidSeries A—Jan 2025
    Spark Pediatrics logoSpark PediatricsUnknown$15MJan 2025
    Noema Pharma logoNoema PharmaSeries B—Dec 2024
    PipCare logoPipCareSeries A$5MOct 2024
    Medicom logoMedicomUnknown—Jul 2024
    Cerevance logoCerevanceSeries C$51MApr 2024
    BrainCheck logoBrainCheckSeries B$15MMar 2024
    Rialtic logoRialticSeries B$37MJan 2024
    Sudo Biosciences logoSudo BiosciencesSeries B$147MJan 2024
    Sudo logoSudoSeries B$147MJan 2024
    Elektra Health logoElektra HealthUnknown$3.3MJan 2024
    Noema logoNoemaSeries B—Jan 2024
    Noema logoNoemaSeries B—Mar 2023
    Noema Pharma logoNoema PharmaSeries B—Mar 2023
    Smile Digital Health logoSmile Digital HealthSeries B$30MJan 2023
    SparingVision logoSparingVisionSeries B—Sep 2022
    Abridge logoAbridgeSeries A$12.5MAug 2022
    IInfectious Disease ConnectUnknown$5.5MJan 2022
    Page 1 of 3

    Top Co-Investors

    The Invus Group, LLC10 shared
    Jeito Capital8 shared
    Sofinnova Partners7 shared
    MPM Capital7 shared
    Longwood Fund6 shared
    Arkin Bio Ventures6 shared
    Alexandria Venture Investments5 shared
    Forbion5 shared
    Gilde Healthcare5 shared
    Polaris Partners5 shared
    Labcorp5 shared
    RA Capital Management4 shared
    4BIO Capital4 shared
    Norwest Venture Partners3 shared
    Sanofi Ventures3 shared
    Foresite Capital3 shared
    Illumina Ventures3 shared
    The Blue Venture Fund3 shared
    GV3 shared
    S3 Ventures3 shared

    Last updated: 20 October 2026