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    UPMC Enterprises

    Pittsburgh, Pennsylvania, United StatesFounded 2014
    enterprises.upmc.comLinkedIn
    HealthcareBiotech & Life Sciences

    UPMC Enterprises is the innovation, commercialization, and venture capital arm of UPMC, a $28 billion health care provider and insurer based in Pittsburgh, PA. It invests in digital health solutions and translational sciences, including therapeutics, diagnostics, and medical devices, having committed $1 billion to life sciences investments.

    37% of their portfolio is in Healthcare. Deal activity decreased year-over-year (3 deals in the last 12 months vs 6 prior). Their most common stage is series-b (41% of deals). Average disclosed round size is $57.0M (across 30 rounds with reported amounts).

    Find people at UPMC Enterprises on Goldilocks AI

    Portfolio

    36

    Fund Size

    $1B

    Top Stage

    Series B

    Last 12 Mo

    2

    Team

    David Okonkwo, MD, PhD

    David Okonkwo, MD, PhD

    Executive Vice President

    José-Alain Sahel, MD

    José-Alain Sahel, MD

    Executive Vice President

    Matthias Kleinz, DVM, PhD

    Matthias Kleinz, DVM, PhD

    Executive Vice President, UPMC Enterprises

    Nicole Ansani, PharmD

    Nicole Ansani, PharmD

    Senior Vice President, New Development Initiatives

    MJ

    Maryam Jalal, MS

    Senior Associate, Transaction Services

    Portfolio Breakdown

    Stage Distribution

    Sector Distribution

    Investment Activity

    DealsAvg Round Size

    Portfolio

    41 investments
    CompanyRoundAmountDate
    Precede Biosciences logoPrecede BiosciencesSeries B$63.5MJan 2026
    Penguin AI logoPenguin AISeries A$29.7MSep 2025
    Ultromics logoUltromicsSeries C$55MJul 2025
    Carta Healthcare logoCarta HealthcareSeries B$18.3MMay 2025
    Latigo Biotherapeutics logoLatigo BiotherapeuticsSeries B$150MMar 2025
    Ouro Medicines logoOuro MedicinesSeries A$120MJan 2025
    Spark Pediatrics logoSpark PediatricsUnknown$15MJan 2025
    Noema Pharma logoNoema PharmaSeries B—Dec 2024
    PPipCareSeries A$5MOct 2024
    Medicom Technologies logoMedicom TechnologiesUnknown—Jul 2024
    BrainCheck logoBrainCheckSeries B$15MMar 2024
    Sudo Biosciences logoSudo BiosciencesSeries B$147MJan 2024
    Sudo logoSudoSeries B$147MJan 2024
    Elektra Health logoElektra HealthUnknown$3.3MJan 2024
    Noema logoNoemaSeries B—Jan 2024
    Noema logoNoemaSeries B—Mar 2023
    NNoema Pharma AGSeries B—Mar 2023
    Smile Digital Health logoSmile Digital HealthSeries B$30MJan 2023
    SparingVision logoSparingVisionSeries B—Sep 2022
    Abridge logoAbridgeSeries A$12.5MAug 2022
    Smile CDR logoSmile CDRSeries A$20MAug 2021
    Ring Therapeutics logoRing TherapeuticsSeries B$117MJul 2021
    Ring logoRingSeries B$117MJul 2021
    SEMPRE logoSEMPRESeries A$14.3MJun 2021
    WWerewolf TherapeuticsSeries B$72MJan 2021
    Page 1 of 2

    Top Co-Investors

    The Invus Group, LLC10 shared
    Jeito Capital8 shared
    Sofinnova Partners7 shared
    Alexandria Venture Investments5 shared
    Forbion5 shared
    Gilde Healthcare5 shared
    Polaris Partners5 shared
    Labcorp5 shared
    4BIO Capital4 shared
    Norwest Venture Partners3 shared
    Sanofi Ventures3 shared
    Monograph Capital3 shared
    T. Rowe Price3 shared
    Flagship Pioneering3 shared
    Altitude Life Science Ventures3 shared
    Bpifrance3 shared
    Ysios Capital3 shared
    Learn Capital2 shared
    Kaiser Permanente Ventures2 shared
    Sands Capital2 shared

    Last updated: 8 September 2026