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    Woodline Partners

    San Francisco, California, United StatesFounded 2018

    Woodline Partners is a hedge fund that employs a market-neutral, long/short equity strategy, focusing on generating "idiosyncratic alpha" through bottom-up fundamental research. They primarily invest in the healthcare, technology, and industrial sectors, utilizing shorts to hedge market risk.

    50% of their portfolio is in Biotech & Life Sciences. Deal activity decreased year-over-year (2 deals in the last 12 months vs 3 prior). Their most common stage is series-b (42% of deals). Average disclosed round size is $148.2M (across 11 rounds with reported amounts).

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    Portfolio

    12

    Fund Size

    Top Stage

    Series B

    Last 12 Mo

    2

    Portfolio Breakdown

    Stage Distribution

    Sector Distribution

    Investment Activity

    DealsAvg Round Size

    Portfolio

    12 investments
    CompanyRoundAmountDate
    Skyryse logoSkyryseSeries CFeb 2026
    SSAB Biotherapeutics, Inc.Series B$175MJul 2025
    Elektrofi, Inc. logoElektrofi, Inc.Series C$112.3MOct 2024
    Blue Earth Therapeutics Ltd logoBlue Earth Therapeutics LtdSeries A$76.5MOct 2024
    Formo logoFormoSeries B$61MSep 2024
    BBuild A Rocket BoySeries D$110MJan 2024
    Odyssey Therapeutics, Inc. logoOdyssey Therapeutics, Inc.Series B$168MOct 2022
    Odyssey Therapeutics, Inc. logoOdyssey Therapeutics, Inc.Series A$218MDec 2021
    Arbor Biotechnologies Inc logoArbor Biotechnologies IncSeries B$215MNov 2021
    SmartNews logoSmartNewsSeries F$230MSep 2021
    Affinia Therapeutics logoAffinia TherapeuticsSeries B$110MMay 2021
    Patreon logoPatreonGrowth$155MApr 2021

    Top Co-Investors

    SR One3 shared
    OrbiMed2 shared
    Colt Ventures2 shared
    ArrowMark Partners2 shared
    Janus Henderson Investors2 shared
    Princeville Capital1 shared
    ACA Investments1 shared
    Green Co-Invest Investment1 shared
    Yamauchi-No.10 Family Office1 shared
    SMBC Venture Capital1 shared

    Last updated: 16 April 2026