The Blue Venture Fund invests in healthcare technology, services, and clinical sciences companies to drive better health outcomes and deliver superior value to patients. Their strategy involves a unique partnership among Blue Cross Blue Shield companies, focusing on long-term strategic collaborations to foster innovation and commercialize solutions within the healthcare ecosystem.
89% of their portfolio is in Healthcare. Deal activity increased 67% year-over-year (5 deals in the last 12 months). Average disclosed round size is $47.8M (across 16 rounds with reported amounts).
Portfolio
19
Fund Size
$1B
Top Stage
Series A
Last 12 Mo
5
Team
ES
Emir Sandhu
Managing Director
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
19 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 Big Health | Unknown | $23.7M | Feb 2026 |
 Origin | Series B | — | Jan 2026 |
 Nest Health | Series A | $12.5M | Oct 2025 |
 Daymark Health | Series A | $20M | Sep 2025 |
 Ultromics | Series C | $55M | Jul 2025 |
| UUpward Health | Series C | — | Jan 2025 |
 Fort Health | Series A | $5.5M | Nov 2024 |
| TTuesday Health | Series C | $60M | May 2024 |
 Sempre Health | Series B | $20M | Sep 2023 |
 Limber Health | Series A | $11M | Oct 2022 |
 Path | Series A | $30M | Sep 2022 |
| SSomatus | Series E | $325M | Feb 2022 |
 Wayspring | Growth | $75M | Sep 2021 |
| Ultromics | Series B | $33M | Aug 2021 |
 Bluestone Physician Services | Unknown | — | Aug 2021 |
| Sempre Health | Series B | $15M | Jun 2021 |
 Insightin Health | Series A | $12M | Feb 2021 |
| SSomatus | Series C | $64M | Jun 2020 |
| AArtspace | Series A | $2.5M | Jan 2012 |
Top Co-Investors
Optum Ventures3 shared
Valtruis2 shared
GV (Google Ventures)2 shared
.406 Ventures2 shared
Deerfield Management Company2 shared
Flare Capital Partners2 shared
Longitude Capital2 shared
Industry Ventures1 shared
Mass General Brigham Ventures1 shared
Allegis1 shared
Lightrock1 shared
Oxford Science Enterprises1 shared
UPMC Enterprises1 shared
Altos Ventures1 shared
Hartbeat Ventures1 shared
AlleyCorp1 shared
CVS Health1 shared
Gilde Healthcare1 shared
8VC1 shared
Amboy Street Ventures1 shared
Last updated: 15 April 2026