.406 Ventures is an early-stage venture capital firm that focuses on seed and Series A investments in enterprise-focused companies within the healthcare, data + AI, and cybersecurity sectors. Their strategy is thesis-driven, involving extensive market research and engagement with Fortune 100 buyers to identify critical problems and emerging trends, and they aim to be hands-on partners, providing support beyond just capital.
Portfolio
3
Fund Size
$1.1M
Top Stage
Series C
Last 12 Mo
0
Stage Distribution
Portfolio
3 investments
| Company | Round | Amount | Date |
|---|---|---|---|
| Indico Data | Series A | $19M | Jun 2024 |
| Simon Data | Series D | $54M | Aug 2023 |
| Cortica, Inc. | Series C | $60M | Jun 2021 |
Top Co-Investors
Longitude Capital1 shared
Aperture Venture Partners1 shared
Silicon Valley Bank1 shared
Macquarie Capital1 shared
Polaris Venture Partners1 shared
F-Prime Capital1 shared
Sandbox Industries1 shared
Jump Capital1 shared
Last updated: 27 February 2026