Delos Capital is a New York-based private equity firm that invests in lower middle-market companies across the United States. The firm focuses on management buyouts, recapitalizations, and growth investments in sectors including chemicals, packaging, industrials, and consumer products.
38% of their portfolio is in Biotech & Life Sciences. Deal activity decreased year-over-year (3 deals in the last 12 months vs 5 prior). Average disclosed round size is $108.8M (across 41 rounds with reported amounts).
Portfolio
29
Fund Size
—
Top Stage
Series B
Last 12 Mo
3
Team
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
45 investments
| Company | Round | Amount | Date |
|---|---|---|---|
| AAlpha-9 | Series C | $175M | Sep 2026 |
| TTRexBio, Inc. | Series C | $50M | Jan 2026 |
 STRM.BIO | Seed | $8M | Jan 2026 |
 Trex Bio | Unknown | $50M | Jan 2026 |
 Avenzotx | Series B | $60M | Sep 2025 |
 Avenzo Therapeutics | Series B | $60M | Jan 2025 |
| Avenzo Therapeutics | Unknown | $386M | Nov 2024 |
| Avenzotx | Unknown | $386M | Nov 2024 |
| AAlpha-9 Oncology, Inc. | Series C | $175M | Oct 2024 |
| AAlpha-9 | Series C | $175M | Oct 2024 |
 Cardurion Pharmaceuticals | Series B | $260M | Jul 2024 |
| EExsilio Therapeutics | Series A | $82M | Jun 2024 |
 Avernatx | Series A | $82M | Jun 2024 |
 Zenas BioPharma | Series C | $200M | May 2024 |
| Zenas BioPharma | Series C | $200M | Jan 2024 |
| AAverna Therapeutics | Series A | $82M | Jan 2024 |
| Avernatx | Series A | $82M | Jan 2024 |
| AAverna | Series A | $82M | Jan 2024 |
| AAlpha-9 Oncology, Inc. | Series C | $175M | Jan 2024 |
| EExsilio Therapeutics | Series A | $82M | Jan 2024 |
 Sirius Therapeutics | Series B | $50M | Oct 2023 |
| EEccogene | Series B | — | Jun 2023 |
 Ensoma | Series B | $135M | May 2023 |
 Ostial Corporation | Series C | $7.5M | Feb 2023 |
 Instylla | Unknown | $30M | Jan 2023 |
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Top Co-Investors
OrbiMed14 shared
RA Capital Management8 shared
New Enterprise Associates7 shared
Insight Partners6 shared
The Invus Group, LLC6 shared
SR One6 shared
Quan Funds6 shared
Innovation Endeavors5 shared
Arc Ventures5 shared
Deep Insight5 shared
Digitalis Ventures5 shared
Longitude Capital5 shared
Foresite Capital5 shared
Domain Associates5 shared
Pontifax4 shared
Sixty Degree Capital4 shared
Amzak Health4 shared
LifeSci Venture Partners4 shared
Soleus Capital4 shared
Last updated: 20 October 2026