Delos Capital is a New York-based private equity firm that invests in lower middle-market companies across the United States. The firm focuses on management buyouts, recapitalizations, and growth investments in sectors including chemicals, packaging, industrials, and consumer products.
37% of their portfolio is in Biotech & Life Sciences. Deal activity decreased year-over-year (3 deals in the last 12 months vs 6 prior). Average disclosed round size is $114.5M (across 34 rounds with reported amounts).
Portfolio
29
Fund Size
—
Top Stage
Series B
Last 12 Mo
4
Team
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
35 investments
| Company | Round | Amount | Date |
|---|---|---|---|
| TTRexBio, Inc. | Series C | $50M | Jan 2026 |
 STRM.BIO | Seed | $8M | Jan 2026 |
 Trex Bio | Unknown | $50M | Jan 2026 |
 Avenzo | Series B | $60M | Sep 2025 |
 Avenzo Therapeutics | Series B | $60M | Jan 2025 |
| Avenzo Therapeutics | Unknown | $386M | Nov 2024 |
| Avenzo | Unknown | $386M | Nov 2024 |
 Alpha-9 Oncology | Series C | $175M | Oct 2024 |
| AAlpha-9 Oncology, Inc. | Series C | $175M | Oct 2024 |
| AAlpha-9 | Series C | $175M | Oct 2024 |
 Cardurion Pharmaceuticals | Series B | $260M | Jul 2024 |
| EExsilio Therapeutics | Series A | $82M | Jun 2024 |
| AAverna Therapeutics | Series A | $82M | Jan 2024 |
 Averna Tx | Series A | $82M | Jan 2024 |
| AAverna | Series A | $82M | Jan 2024 |
| AAlpha-9 Oncology, Inc. | Series C | $175M | Jan 2024 |
 Sirius Therapeutics | Series B | $50M | Oct 2023 |
| EEccogene | Series B | — | Jun 2023 |
 Ensoma | Series B | $135M | May 2023 |
| OOstial Corporation | Series C | $7.5M | Feb 2023 |
| RRejoni, Inc. | Series B | $25M | Dec 2022 |
| RRgenta | Series A | $52M | Nov 2022 |
 Antios Therapeutics | Series B | $75M | Nov 2021 |
| AAntios Therapeutics, Inc. | Series A | $75M | Nov 2021 |
| AAntios Therapeutics, Inc. | Series B | $96M | Apr 2021 |
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Top Co-Investors
OrbiMed11 shared
RA Capital Management8 shared
New Enterprise Associates6 shared
Longitude Capital5 shared
Digitalis Ventures5 shared
The Invus Group, LLC5 shared
SR One5 shared
Quan Funds5 shared
Foresite Capital5 shared
General Catalyst4 shared
Samsara BioCapital4 shared
Frazier Life Sciences4 shared
Lightspeed Venture Partners4 shared
Pontifax4 shared
Sixty Degree Capital4 shared
Amzak Health4 shared
LifeSci Venture Partners4 shared
Soleus Capital4 shared
Innovation Endeavors4 shared
Arc Ventures4 shared
Last updated: 8 September 2026