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    Duke Capital Partners logo

    Duke Capital Partners

    Durham, North Carolina, United StatesFounded 2015
    dukecapitalpartners.duke.eduLinkedIn
    AIBiotech & Life SciencesFintechHealthcare

    Duke Capital Partners is a venture capital firm that focuses on investing in early-stage, Duke-affiliated startups with high growth potential and the ability to generate venture-scale returns. The firm primarily targets companies in the consumer, enterprise, and life science sectors.

    40% of their portfolio is in AI. Their most common stage is series-a (40% of deals). Average disclosed round size is $69.2M (across 4 rounds with reported amounts).

    Find people at Duke Capital Partners on Goldilocks AI

    Portfolio

    5

    Fund Size

    $105M

    Top Stage

    Series A

    Last 12 Mo

    2

    Portfolio Breakdown

    Stage Distribution

    Sector Distribution

    Investment Activity

    DealsAvg Round Size

    Portfolio

    5 investments
    CompanyRoundAmountDate
    Ten63 Therapeutics logoTen63 TherapeuticsUnknown—Feb 2026
    Eloquent AI logoEloquent AISeed$7.4MSep 2025
    Liquid AI logoLiquid AISeries A$250MDec 2024
    DANNCE.AI logoDANNCE.AIPre-Seed$2.6MNov 2024
    SiPhox Health logoSiPhox HealthSeries A$17M—

    Top Co-Investors

    LDV Capital1 shared
    Glasswing Ventures1 shared
    AMD Ventures1 shared
    OSS Capital1 shared
    Khosla Ventures1 shared
    Intel Capital1 shared
    Alumni Ventures Group1 shared
    MetaPlanet1 shared
    Shorewind Capital1 shared
    LongeVC1 shared
    Overlap Holdings1 shared
    Chugai Venture Fund1 shared
    Gates Foundation1 shared
    K5 Global1 shared
    Black Opal Ventures1 shared
    Yosemite1 shared
    Morpheus Ventures1 shared
    Alexandria Venture Investments1 shared
    Draper Associates1 shared
    Foundation Capital1 shared

    Last updated: 18 March 2026