Freeflow Ventures is an early-stage venture capital firm focused on deep tech solutions to human and planetary health challenges, enabled by AI and ML. The firm invests in science-driven companies originating from Caltech and Berkeley.
42% of their portfolio is in Biotech & Life Sciences. Deal activity decreased year-over-year (2 deals in the last 12 months vs 3 prior). Their most common stage is series-a (50% of deals). Average disclosed round size is $26.3M (across 23 rounds with reported amounts).
Portfolio
21
Fund Size
$90M
Top Stage
Series A
Last 12 Mo
2
Team
DF
David Fleck
Founder & Managing Partner
SR
Steve Roy
Operating Partner
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
26 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 Erg Bio | Seed | $6.5M | Nov 2025 |
 PINC Technologies Inc. | Seed | $6.8M | Oct 2025 |
 Mitico | Seed | $4.3M | Feb 2025 |
| EEsperto | Series A | $15.2M | Feb 2025 |
 Esperto Medical | Series A | — | Feb 2025 |
| Esperto Medical | Series A | $15.2M | Jan 2025 |
 Holoclara | Series A | $16M | Jun 2024 |
 Tierra Biosciences | Series A | $11.4M | Mar 2024 |
| Holoclara | Series A | $16M | Jan 2024 |
| Tierra Biosciences | Series A | $11.4M | Jan 2024 |
 Iambic Therapeutics | Series B | $220M | Jan 2024 |
 Membrion | Series B | $7M | Jan 2023 |
 H2U Technologies | Series A | $11M | Mar 2022 |
 Hydrosat | Seed | $10M | Nov 2021 |
 Appia Bio | Series A | $52M | May 2021 |
| H2U Technologies | Series A | $7M | Jan 2021 |
| Appia Bio | Series A | $52M | Jan 2021 |
 Aralez Bio | Series A | $12M | — |
 Vivere Oncotherapies | Unknown | $10M | — |
 Calicat | Unknown | $3M | — |
 Miist Therapeutics | Seed | $7M | — |
 StrokeDx | Seed | $5M | — |
 Miist Therapeutics | Seed | $7M | — |
 Captura Corp | Series A | — | — |
| IIambic Ai | Series B | $100M | — |
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Top Co-Investors
Bold Capital Partners4 shared
Dolby Family Ventures3 shared
Maverick Ventures3 shared
Health Catalyst Capital3 shared
Wavemaker Three-Sixty Health3 shared
SOSV2 shared
Horizons Ventures2 shared
private angel investors2 shared
Material Impact2 shared
Creative Ventures2 shared
Hillspire2 shared
Social Capital2 shared
Prosus Ventures2 shared
Sherpa Healthcare Partners2 shared
8VC2 shared
Two Sigma Ventures2 shared
VoLo Earth Ventures2 shared
Refactor Capital2 shared
1517 Fund2 shared
Catalio Capital Management2 shared
Last updated: 20 October 2026