Frist Cressey Ventures is a venture capital firm on a mission to accelerate the growth of companies changing the face of healthcare. Founded in 2016 by Senator Bill Frist, M.D. and Bryan Cressey, the firm invests in early-stage startups building technology or tech-enabled services to advance quality of care, system integration, and patient outcomes.
83% of their portfolio is in Healthcare. Deal activity decreased year-over-year (4 deals in the last 12 months vs 8 prior). Average disclosed round size is $71.8M (across 50 rounds with reported amounts).
Portfolio
34
Fund Size
$425M
Top Stage
Series A
Last 12 Mo
4
Team
Harrison Frist
Operating Partner
J. Mark Tipps
PARTNER & COO
William Trapnell
Senior Associate
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
58 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 Thyme | Series E | $125M | Sep 2026 |
 Qualified Health | Series A | — | Mar 2026 |
 Chamber Cardio | Series A | $60M | Feb 2026 |
 Devoted Health, Inc. | Series F | $317M | Jan 2026 |
| Devoted Health, Inc. | Series F | $317M | Jan 2026 |
| Devoted Health, Inc. | Series F | $48M | Nov 2025 |
 Thyme Care | Series D | $97M | Sep 2025 |
| Thyme | Series D | $97M | Sep 2025 |
 Ambience | Series C | $243M | Jul 2025 |
 Ambience | Series C | — | Jul 2025 |
 Carta Healthcare | Series B | $18.3M | May 2025 |
 Bicycle Health | Series B | $16.5M | Jan 2025 |
 Oshi Health | Series C | $60M | Jan 2025 |
 Qualified Health | Seed | $30M | Jan 2025 |
| Qualified Health | Seed | $30M | Jan 2025 |
 Aradigm | Series A | $20M | Jan 2025 |
 Ambience Healthcare, Inc. | Series C | $243M | Jan 2025 |
| Devoted Health, Inc. | Series F | $48M | Jan 2025 |
| AAradigm Health | Series A | $20M | Jan 2025 |
| Ambience | Series C | $243M | Jan 2025 |
| Oshi Health | Series C | — | Oct 2024 |
| Thyme Care | Series C | $95M | Jul 2024 |
| Thyme Care | Series E | — | May 2024 |
 Praia Health | Series A | $20M | Apr 2024 |
 Blackbird Health | Series A | $17M | Feb 2024 |
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Top Co-Investors
Flare Capital Partners12 shared
Andreessen Horowitz12 shared
CVS Health11 shared
Transformation Capital10 shared
AlleyCorp10 shared
Morgan Health10 shared
SignalFire8 shared
General Catalyst7 shared
Optum Ventures7 shared
SpringRock Ventures7 shared
Foresite Capital6 shared
Oak HC/FT6 shared
Iconiq Capital, LLC6 shared
Kaiser Permanente Ventures6 shared
Concord Health Partners5 shared
Humana5 shared
Memorial Hermann Health System5 shared
Mass General Brigham Ventures5 shared
Providence Ventures5 shared
Last updated: 7 October 2026