Osage University Partners (OUP) is a venture capital firm that invests in science-driven startups emerging from the world's leading research labs and innovation ecosystems. Founded in 2009 and headquartered in Bala Cynwyd, Pennsylvania, OUP manages over $800 million and has invested in more than 150 life science and technology startups.
32% of their portfolio is in Biotech & Life Sciences. Deal activity decreased year-over-year (3 deals in the last 12 months vs 7 prior). Average disclosed round size is $55.1M (across 132 rounds with reported amounts).
Portfolio
100
Fund Size
$800M
Top Stage
Series A
Last 12 Mo
3
Team
Matt Cohen
Managing Partner
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
148 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 Terremoto Biosciences | Series C | $108M | Apr 2026 |
 Precede Bio | Series B | $63.5M | Jan 2026 |
 Eridu AI | Unknown | $200M | Jan 2026 |
 Addition Therapeutics | Unknown | $100M | Dec 2025 |
 Neuros Medical | Series D | $56M | Jul 2025 |
 Neuros | Series D | $56M | Jul 2025 |
 Virtue AI | Seed | — | Apr 2025 |
| Virtue AI | Series A | $30M | Apr 2025 |
 Atsena Therapeutics | Series C | $150M | Apr 2025 |
| AAtsena | Series C | $150M | Apr 2025 |
 Overland AI | Series A | — | Jan 2025 |
 AssetWatch | Series C | $75M | Jan 2025 |
| Neuros | Series A | $56M | Jan 2025 |
| Atsena Therapeutics | Series C | $150M | Jan 2025 |
| QQuintessent Inc. | Seed | $11.5M | Mar 2024 |
| AssetWatch | Series B | $38M | Jan 2024 |
| Precede Bio | Series A | $57M | Oct 2023 |
 Kate | Series A | $51M | Jun 2023 |
| KKate Therapeutics | Series A | $51M | Jun 2023 |
 Chroma Medicine | Series B | $135M | Mar 2023 |
 Hack The Box | Series C | $55M | Jan 2023 |
 Opsys | Series C | $51.5M | Jan 2023 |
| KKate Therapeutics | Series A | $51M | Jan 2023 |
 MicroTransponder | Series E | $73M | Sep 2022 |
 Delfi Diagnostics, Inc. | Series B | — | Jul 2022 |
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Top Co-Investors
OrbiMed24 shared
Sofinnova Partners14 shared
RA Capital Management14 shared
Alexandria Venture Investments11 shared
Abingworth LLP10 shared
Canaan Partners10 shared
Wellington Management9 shared
Illumina Ventures9 shared
U.S. Venture Partners9 shared
Lightstone Ventures9 shared
New Enterprise Associates9 shared
InterWest Partners9 shared
Sutter Hill Ventures9 shared
Cormorant Asset Management8 shared
Frazier Healthcare Partners8 shared
Pfizer Ventures7 shared
Aperture Venture Partners7 shared
Rock Springs Capital7 shared
LAV6 shared
Agent Capital6 shared
Last updated: 7 October 2026