U.S. Venture Partners (USVP) is a Silicon Valley-based venture capital firm founded in 1981, partnering with entrepreneurs to build world-class companies. The firm focuses on early-stage investments in enterprise software, cybersecurity, consumer, and healthcare, and is currently investing out of its thirteenth fund, USVP XIII.
Deal activity increased 40% year-over-year (7 deals in the last 12 months). Average disclosed round size is $40.7M (across 105 rounds with reported amounts).
Portfolio
88
Fund Size
$400M
Top Stage
Series B
Last 12 Mo
6
Team
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
113 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 Route 92 Medical | Growth | $50M | Apr 2026 |
 Slang Ai | Series B | $36M | Feb 2026 |
 Adaptive6 | Series A | $28M | Jan 2026 |
 Maneva | Series A | $27M | Jan 2026 |
 Apono | Series B | $34M | Nov 2025 |
 Sparrow Pharmaceuticals | Series B | $95M | Sep 2025 |
 Iantrek, Inc | Series C | $42M | Aug 2025 |
 Neuros Medical | Series D | $56M | Jul 2025 |
 Mealogic, Inc. | Series B | $16M | Jun 2025 |
 Shoulder Innovations | Series E | $40M | Mar 2025 |
 Nervonik | Series A | $13M | Mar 2025 |
 Delfina | Series A | $17M | Jan 2025 |
 Okami Medical | Unknown | $32.5M | Oct 2024 |
| Route 92 Medical | Series F | $50M | Sep 2024 |
 IONIX | Series A | $15M | Feb 2024 |
 Stensul | Series C | $34.5M | Nov 2023 |
 Percepto | Series C | $67M | Jun 2023 |
| SSurgical Safety Technologies | Series A | $15M | May 2023 |
 Heartflow | Series F | $215M | Apr 2023 |
| IONIX | Series A | $27M | Mar 2023 |
 Luminopia | Series A | $16M | Jan 2023 |
 HealthJoy | Series D | $60M | Oct 2022 |
 SecuriThings | Series B | $21M | Oct 2022 |
 MicroTransponder | Series E | $73M | Sep 2022 |
 Oliver Space | Series B | $36M | Aug 2022 |
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Top Co-Investors
Nexus Venture Partners14 shared
The Vertical Group11 shared
Norwest Venture Partners8 shared
Uncork Capital7 shared
Battery Ventures7 shared
First Round Capital7 shared
Venrock6 shared
Chicago Ventures5 shared
Osage University Partners5 shared
OrbiMed5 shared
Versant Ventures5 shared
Shasta Ventures4 shared
CRV4 shared
Sectoral Asset Management4 shared
Morgenthaler Ventures4 shared
XYZ Venture Capital3 shared
Aperture Venture Partners3 shared
Team83 shared
Hyperwise Ventures3 shared
Last updated: 7 September 2026