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    PX

    Perceptive Xontogeny Venture Fund

    New York, New York, United StatesFounded 2018

    The Perceptive Xontogeny Venture Fund (PXV Fund) focuses on early-stage life sciences companies, primarily making seed and Series A investments, with a select focus on later-stage financings. Its strategy involves partnering with founders and entrepreneurs, providing operational and strategic support, and investing in differentiated technologies that aim to significantly impact serious diseases or improve healthcare delivery. The fund targets investments in biotechnology, medtech, healthtech, digital health, and healthcare tools/services, with a data-driven approach to advance technologies from preclinical stages through clinical proof-of-concept.

    75% of their portfolio is in Biotech & Life Sciences. Deal activity increased 100% year-over-year (4 deals in the last 12 months). Average disclosed round size is $106.4M (across 8 rounds with reported amounts).

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    Portfolio

    8

    Fund Size

    $725M

    Top Stage

    Series A

    Last 12 Mo

    4

    Team

    GH

    Gianna Hoffman-Luca, Ph.D.

    Partner

    Portfolio Breakdown

    Stage Distribution

    Sector Distribution

    Investment Activity

    DealsAvg Round Size

    Portfolio

    8 investments
    CompanyRoundAmountDate
    Crystalys Therapeutics Inc. logoCrystalys Therapeutics Inc.Series A$205MSep 2025
    Mercy BioAnalytics, Inc. logoMercy BioAnalytics, Inc.Series B$59MSep 2025
    Galvanize Therapeutics logoGalvanize TherapeuticsSeries C$100MSep 2025
    Zucara Therapeutics Inc. logoZucara Therapeutics Inc.Series B$25MMay 2025
    CereVasc, Inc. logoCereVasc, Inc.Series B$70MMay 2024
    Adaptilens, Inc. logoAdaptilens, Inc.Series A$17.5MApr 2024
    Avalyn Pharma Inc. logoAvalyn Pharma Inc.Series C$175MSep 2023
    CCARGO Therapeutics, Inc.Series A$200MMar 2023

    Top Co-Investors

    Ally Bridge Group2 shared
    Janus Henderson Investors2 shared
    KB Partners1 shared
    Pontifax1 shared
    Wedbush Healthcare Partners1 shared
    Sanofi Ventures1 shared
    Sozo Ventures1 shared
    iSelect Fund1 shared
    Portfolia1 shared
    Labcorp1 shared
    Bain Capital Life Sciences1 shared
    Sofinnova Partners1 shared

    Last updated: 12 April 2026