Perceptive Xontogeny Venture Fund
The Perceptive Xontogeny Venture Fund (PXV Fund) focuses on early-stage life sciences companies, primarily making seed and Series A investments, with a select focus on later-stage financings. Its strategy involves partnering with founders and entrepreneurs, providing operational and strategic support, and investing in differentiated technologies that aim to significantly impact serious diseases or improve healthcare delivery. The fund targets investments in biotechnology, medtech, healthtech, digital health, and healthcare tools/services, with a data-driven approach to advance technologies from preclinical stages through clinical proof-of-concept.
75% of their portfolio is in Biotech & Life Sciences. Deal activity increased 100% year-over-year (4 deals in the last 12 months). Average disclosed round size is $106.4M (across 8 rounds with reported amounts).
Portfolio
8
Fund Size
$725M
Top Stage
Series A
Last 12 Mo
4
Team
Gianna Hoffman-Luca, Ph.D.
Partner
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
Portfolio
| Company | Round | Amount | Date |
|---|---|---|---|
| Series A | $205M | Sep 2025 | |
| Series B | $59M | Sep 2025 | |
| Series C | $100M | Sep 2025 | |
| Series B | $25M | May 2025 | |
| Series B | $70M | May 2024 | |
| Series A | $17.5M | Apr 2024 | |
| Series C | $175M | Sep 2023 | |
| CCARGO Therapeutics, Inc. | Series A | $200M | Mar 2023 |
Top Co-Investors
Last updated: 12 April 2026