Protocol Labs is an innovation network that connects over 750 tech startups, service providers, investment funds, accelerators, foundations, and open source projects developing breakthrough technologies in computing. Through its PL Capital venture funds, it invests in early-stage founders building the next generation of computing, crypto, AI, and neurotechnology.
Deal activity increased 50% year-over-year (3 deals in the last 12 months). Average disclosed round size is $17.8M (across 93 rounds with reported amounts).
Portfolio
81
Fund Size
—
Top Stage
Seed
Last 12 Mo
3
Team
BH
Brad Holden
Managing Director / Head of Investments
SE
Sean Escola
Venture Partner
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
98 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 Impossible Cloud | Growth | $34M | Jun 2026 |
| Tt54 Labs | Seed | $5M | Feb 2026 |
 Akave | Seed | $6.7M | Jan 2026 |
 Reppo | Strategic | $20M | Jan 2026 |
| Tt54 Labs | Seed | $5M | Jan 2026 |
 Akave | Seed | $6.7M | Jan 2026 |
| NNeurosoft Bioelectronics | Seed | $7.5M | Jan 2026 |
 Enlightra | Unknown | $15M | Dec 2025 |
 FrodoBots | Unknown | $8M | Feb 2025 |
 Sign Protocol | Seed | — | Jan 2025 |
 Graze.social | Pre-Seed | $1M | Jan 2025 |
| Reppo | Unknown | $2.2M | Jan 2025 |
 Blockcast | Unknown | $2.9M | Oct 2024 |
 COMPUTE LABS | Pre-Seed | $3M | Jul 2024 |
 WeatherXM | Series A | $7.7M | May 2024 |
 Prime Intellect | Seed | $5.5M | Apr 2024 |
 Lumino Labs | Pre-Seed | $2.8M | Mar 2024 |
 Zama | Series A | $73M | Mar 2024 |
 Lava Network | Seed | $12M | Jan 2024 |
 DIMO | Series A | $11.5M | Jan 2024 |
 Mountain Protocol | Seed | $8M | Jan 2024 |
 GenLayer | Seed | $7.5M | Jan 2024 |
 Zama | Series A | $73M | Jan 2024 |
| WeatherXM | Seed | $7.7M | Jan 2024 |
| Zama | Series A | $73M | Jan 2024 |
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Top Co-Investors
Y Combinator10 shared
HashKey Capital9 shared
Animoca Brands8 shared
Multicoin Capital7 shared
Coinbase Ventures7 shared
CoinFund7 shared
Metaplanet6 shared
Alumni Ventures5 shared
Placeholder5 shared
Big Brain Holdings5 shared
CMT Digital4 shared
Fenbushi Capital4 shared
LongHash Ventures4 shared
OpenSea Ventures4 shared
Skaala4 shared
Dapper Labs4 shared
Polygon Ventures3 shared
The LAO3 shared
Collab+Currency3 shared
Borderless Capital3 shared
Last updated: 7 October 2026