Protocol Labs primarily focuses its venture capital investments on early-stage computing breakthroughs, with a strong emphasis on Web3, distributed systems, decentralized storage, AI, and open-source technologies. Their strategy involves acting as an innovation network to support startups and accelerate research and development across these frontier technology fields.
Their most common stage is series-a (40% of deals). Average disclosed round size is $25.7M (across 15 rounds with reported amounts).
Portfolio
15
Fund Size
—
Top Stage
Series A
Last 12 Mo
2
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
15 investments
| Company | Round | Amount | Date |
|---|---|---|---|
| AAkave | Seed | $6.7M | Mar 2026 |
 Enlightra | Unknown | $15M | Dec 2025 |
 WeatherXM AG | Series A | $7.7M | May 2024 |
 Prime Intellect | Seed | $5.5M | Apr 2024 |
 Lumino | Pre-Seed | $2.8M | Mar 2024 |
 Zama | Series A | $73M | Mar 2024 |
 Bluesky | Seed | $8M | Jul 2023 |
 Huddle01 | Seed | $2.8M | Apr 2023 |
 QuickNode | Series B | $60M | Jan 2023 |
 Fleek | Series A | $25M | Dec 2022 |
 thirdweb | Series A | $24M | Aug 2022 |
| MMona | Series A | $14.6M | Jul 2022 |
 CyberConnect | Series A | $15M | May 2022 |
 Unstoppable Domains | Unknown | $60M | Mar 2022 |
 ConsenSys | Unknown | $65M | Apr 2021 |
Top Co-Investors
Coinbase Ventures3 shared
Fenbushi Capital2 shared
Polygon Studios2 shared
MetaPlanet2 shared
Blockchange Ventures2 shared
The LAO2 shared
Longhash Ventures2 shared
Distributed Ventures2 shared
Big Brain Holdings2 shared
Collab+Currency2 shared
Y Combinator1 shared
Runa Capital1 shared
Pegasus Tech Ventures1 shared
Draper Associates1 shared
Animoca Brands1 shared
Sky9 Capital1 shared
Delphi Digital1 shared
IOSG1 shared
Tribe1 shared
GGV Capital1 shared
Last updated: 21 April 2026