
Route 66 Ventures is a private investment firm based in Alexandria, Virginia, that backs founders using technology to drive positive change. The firm focuses on early-stage investments in fintech and digital health, providing venture capital and credit solutions for emerging companies.
Average disclosed round size is $27.6M (across 48 rounds with reported amounts).
Portfolio
39
Fund Size
—
Top Stage
Series A
Last 12 Mo
1
Team
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
54 investments
| Company | Round | Amount | Date |
|---|---|---|---|
| Seed | $7.8M | Dec 2025 | |
| Unknown | — | Nov 2024 | |
| Seed | $6.5M | Jan 2024 | |
| Seed | $6.5M | Jan 2024 | |
| Series A | — | Jul 2023 | |
| Series A | $20.2M | Jun 2023 | |
| Series B | $27.6M | Jan 2023 | |
| Series A | $11M | Jan 2023 | |
| Series A | $6.5M | Jan 2023 | |
| Series B | $39M | Dec 2022 | |
| Series A | $30M | Nov 2022 | |
| Seed | $5M | Aug 2022 | |
| OOrdaos Bio | Seed | $5M | Aug 2022 |
| Series A | $30M | Mar 2022 | |
| Seed | $6M | Feb 2022 | |
| Seed | $12.3M | Feb 2022 | |
| Seed | — | Jan 2022 | |
| Seed | $2M | Jan 2022 | |
| Series A | $10.3M | Sep 2021 | |
| Seed | $6M | May 2021 | |
| Series A | $27M | May 2021 | |
| Series B | $16.3M | Mar 2021 | |
| Seed | $1.5M | Jul 2020 | |
| Series A | $12M | Oct 2019 | |
| Series C | $200M | Jan 2019 |
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Top Co-Investors
ACE & Company6 shared
Techstars4 shared
S2G Ventures4 shared
Crosslink Capital4 shared
Anthemis4 shared
Hoxton Ventures3 shared
Leaps by Bayer3 shared
Citi Ventures3 shared
The Goldman Sachs Group, Inc.3 shared
Transamerica3 shared
Palo Santo2 shared
Grok Ventures2 shared
Prime Movers Lab2 shared
GV2 shared
CNH Ventures2 shared
iSelect Fund2 shared
VTC Ventures2 shared
IAG Capital Partners2 shared
Last updated: 7 October 2026