
Sontag Innovation Fund
Ponte Vedra Beach, Florida, United StatesFounded 2021
The Sontag Innovation Fund is a venture philanthropy and impact investment fund and a wholly-owned subsidiary of The Sontag Foundation. Established in 2021, it provides early-stage, high-risk capital to accelerate innovative therapeutics, diagnostics, and technologies aimed at diagnosing, treating, preventing, and curing brain cancer.
40% of their portfolio is in Biotech & Life Sciences. Deal activity decreased year-over-year (2 deals in the last 12 months vs 3 prior). Average disclosed round size is $17.8M (across 4 rounds with reported amounts).
Portfolio
5
Fund Size
—
Top Stage
Unknown
Last 12 Mo
2
Team
SD
Scott Davis
Managing Director
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
Portfolio
5 investments
| Company | Round | Amount | Date |
|---|---|---|---|
| Series A | $8.1M | Sep 2025 | |
| Unknown | $8M | Sep 2025 | |
| AAlpheus | Series B | $52M | May 2025 |
| Seed | $3M | Feb 2025 | |
| Pre-Seed | — | Sep 2024 |
Top Co-Investors
BrightEdge2 shared
Two Bear Capital1 shared
DeepWork Capital1 shared
Mayo Clinic Ventures1 shared
Florida Opportunity Fund1 shared
Keiretsu Forum1 shared
Cancer Research Horizons1 shared
Angular Ventures1 shared
IQ Capital1 shared
New York Angels1 shared
HBS Alumni Angels Association1 shared
HealthQuest Capital1 shared
OrbiMed1 shared
Brain Tumor Investment Fund1 shared
Samsara BioCapital1 shared
Last updated: 7 October 2026