VTC Ventures is a venture capital firm based in Roanoke, Virginia that invests in early-stage life sciences and high-growth technology companies. Primarily funded by Virginia Tech and Carilion Clinic and managed by Middleland Capital, it operates through the VTC Innovation Fund and the VTC Seed Fund.
60% of their portfolio is in Healthcare. Average disclosed round size is $6.6M (across 5 rounds with reported amounts).
Portfolio
4
Fund Size
—
Top Stage
Unknown
Last 12 Mo
0
Team
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
5 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 Empo Health | Unknown | $7M | Jun 2025 |
| Empo Health | Unknown | $7M | Jan 2025 |
 EarthOptics | Series A | $10.3M | Sep 2021 |
| HHardshell | Pre-Seed | $1.1M | — |
 BIOHM | Growth | $7.5M | — |
Top Co-Investors
Gaingels2 shared
Story Ventures2 shared
Ulu Ventures2 shared
S2G Ventures1 shared
Leaps by Bayer1 shared
Citi Ventures1 shared
Route 66 Ventures1 shared
CAV Angels1 shared
private angel investors1 shared
Mojo Partners1 shared
Front Porch Venture Partners1 shared
Felton Group1 shared
Barclays1 shared
Last updated: 19 September 2026