Ridgeback Capital is an actively managed private investment firm founded by Dr. Wayne Holman in 2006, specializing in both securities trading and long-term private investments in the life sciences and biopharma sectors. The firm provides patient capital to private and public healthcare companies developing life-saving and life-changing therapies.
62% of their portfolio is in Biotech & Life Sciences. Average disclosed round size is $100.2M (across 15 rounds with reported amounts).
Portfolio
13
Fund Size
—
Top Stage
Series B
Last 12 Mo
0
Team
CB
Craig Burns
Managing Director
LS
Leo Sternlicht
Managing Director
MM
Matt Mezvinsky
Managing Director
WH
Wayne Holman
Founder & CEO
Portfolio Breakdown
Stage Distribution
Sector Distribution
Investment Activity
DealsAvg Round Size
Portfolio
16 investments
| Company | Round | Amount | Date |
|---|---|---|---|
 Hinge Bio | Series A | $30M | Jan 2025 |
| SSenti Bio | Unknown | $47.6M | Dec 2024 |
| SSenti Bio | Unknown | $1.5M | Jun 2024 |
 Freenome Inc | Series D | $300M | Dec 2021 |
 Quell Therapeutics | Series B | $156M | Nov 2021 |
 Arbor Biotechnologies | Series B | $215M | Nov 2021 |
 Turnstone Biologics | Series D | $80M | Jul 2021 |
 Reverie Labs | Series A | $25M | Feb 2021 |
| Quell Therapeutics | Series B | $156M | Jan 2021 |
 Acepodia | Series B | $47M | Jan 2021 |
| 44DMT | Series C | $75M | Jun 2020 |
 TwinStrand Biosciences | Series A | — | Jan 2020 |
| 44DMT | Series B | $90M | Sep 2018 |
 Precision BioSciences | Series B | $110M | — |
 Caribou Biosciences | Series C | $115M | — |
 Bellicum Pharmaceuticals | Series C | $55M | — |
Top Co-Investors
ArrowMark Partners5 shared
Perceptive Advisors4 shared
Tekla Capital Management4 shared
RA Capital Management3 shared
Cowen Healthcare Investments2 shared
Cormorant Asset Management2 shared
Eventide Asset Management2 shared
T. Rowe Price2 shared
S322 shared
Logos Capital2 shared
Farallon Capital Management2 shared
Surveyor Capital2 shared
Adage Capital Management2 shared
Alexandria Venture Investments2 shared
F-Prime Capital2 shared
PFM Health Sciences2 shared
SV Health Investors2 shared
Jeito Capital2 shared
AlbionVC2 shared
British Patient Capital2 shared
Last updated: 8 September 2026