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    University of Chicago

    Chicago, Illinois, United StatesFounded 1890
    www.uchicago.eduLinkedIn
    AIBiotech & Life SciencesClimate & EnergyRobotics & AutomationHardware & Semiconductors

    The University of Chicago is a private research university whose endowment and startup investment programs back early-stage ventures emerging from its academic ecosystem. Through the UChicago Startup Investment Program and partnerships like Harper Court Ventures (managed by MFV Partners), it has allocated $25 million to invest in startups led by UChicago faculty, students, staff, and alumni, with a focus on deep tech, AI, life sciences, and climate technologies.

    Deal activity decreased year-over-year (1 deal in the last 12 months vs 2 prior). Average disclosed round size is $5.7M (across 50 rounds with reported amounts).

    Find people at University of Chicago on Goldilocks AI

    Portfolio

    45

    Fund Size

    $25M

    Top Stage

    Seed

    Last 12 Mo

    1

    Team

    AJ

    Andrew James, CFA

    Managing Director, Public Equity and Equity Oriented Hedge Funds

    JR

    Joanna Rupp

    Managing Director, Private Equity

    AW

    Andy Ward

    Chief Investment Officer

    Portfolio Breakdown

    Stage Distribution

    Sector Distribution

    Investment Activity

    DealsAvg Round Size

    Portfolio

    55 investments
    CompanyRoundAmountDate
    KeyCare logoKeyCareSeries B$27.4MMar 2026
    CavilinQ logoCavilinQSeed$8.8MJan 2026
    PPayteraUnknown$85KJan 2026
    K1 Semiconductor logoK1 SemiconductorUnknown$50KJul 2025
    OrisDX logoOrisDXSeed$4MJan 2025
    Exactics logoExacticsUnknown$115KJan 2025
    Flow Medical logoFlow MedicalSeed$5MDec 2024
    Flow Medical logoFlow MedicalUnknown$2MDec 2023
    DDwellsy ComSeed$11.5MNov 2023
    KeyCare logoKeyCareSeries A$27MJan 2023
    BiomeSense logoBiomeSensePre-Seed—Jan 2023
    Dwellsy logoDwellsySeed$11.5MJan 2023
    PPippin TitleSeed$3MJan 2023
    FarmRaise logoFarmRaiseSeed$7.2MJan 2022
    Electrochaea logoElectrochaeaSeries D—Jan 2022
    Rosita logoRositaSeed$2.4MJan 2022
    RRosita LongevitySeed$2.4MJan 2022
    Andes logoAndesSeed$1MDec 2021
    Andes logoAndesUnknown$660KJun 2021
    FFoxtrot MarketSeries B$42MFeb 2021
    Foxtrot logoFoxtrotSeries B—Feb 2021
    PPippin TitleSeed$5MJan 2021
    AddGraft Therapeutics logoAddGraft TherapeuticsPre-Seed$110KJan 2021
    Tovala logoTovalaSeries B$20MJun 2020
    Foxtrot logoFoxtrotGrowth$17MFeb 2020
    Page 1 of 3

    Top Co-Investors

    Bluestein Ventures4 shared
    Collaborative Fund3 shared
    Wittington Ventures3 shared
    Imaginary Ventures3 shared
    Wasson Enterprise3 shared
    Fifth Wall3 shared
    Lerer Hippeau3 shared
    Ulu Ventures3 shared
    Seedcamp3 shared
    Ship2B Ventures3 shared
    JME Ventures3 shared
    Kfund3 shared
    Gaingels3 shared
    M Ventures2 shared
    Rise of the Rest Seed Fund2 shared
    Monogram Capital Partners2 shared
    Almanac Insights2 shared
    8VC2 shared
    LRVHealth2 shared
    WellSpan Health2 shared

    Last updated: 7 October 2026