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    Investment Firms in Minneapolis, Minnesota, United States

    A significant venture capital and startup hub in the Upper Midwest, it is distinguished by its deep-rooted strengths in healthcare, biotechnology, and medical devices, largely fueled by major corporate anchors and world-class academic institutions. The ecosystem is characterized by a concentration of later-stage venture funding and a mature network supporting scalable companies in its core sectors. Its historical significance is tied to a legacy of corporate innovation and spin-offs, creating a stable foundation for high-growth enterprises.

    Minneapolis, Minnesota, United States's investment landscape is shaped by Healthcare, with 62% of its 13 investment firms focused on this sector. The most active by portfolio size are Arthur Ventures, Matchstick Ventures, and Bread & Butter Ventures.

    Healthcare dominates the investment landscape in Minneapolis, with 62% of investment firms focused on this sector.

    Minneapolis is a particularly strong hub for early-stage investing, with over 69% of investment firms active at the Seed or Pre-Seed stage.

    Last updated: 9 September 2026

    Investment Firms

    13

    Total Investments

    240

    Top Sector

    Healthcare

    Top Stage

    Series A

    Top Investment Sectors in Minneapolis

    The most popular sector focus among Minneapolis investment firms is Healthcare, with 8 investment firms (62%) investing in the space. This is followed by SaaS (4), Enterprise Software (4), Food & Agriculture (4), Fintech (3).

    Investment Stages in Minneapolis

    Minneapolis investment firms are most active at the Series A stage (10 investment firms). This is followed by Series B (10), Seed (9), Growth (8), Series C (7).

    Arthur Ventures logo

    Arthur Ventures

    Minneapolis, Minnesota, United States

    59 investments

    Series A, Series B

    SaaS, Enterprise Software, Cybersecurity

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    Matchstick Ventures logo

    Matchstick Ventures

    Minneapolis, Minnesota, United States

    47 investments

    Seed, Series A

    SaaS

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    Bread & Butter Ventures logo

    Bread & Butter Ventures

    Minneapolis, Minnesota, United States

    29 investments

    Seed, Series A

    Food & Agriculture, Healthcare, SaaS

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    University of Minnesota logo

    University of Minnesota

    Minneapolis, Minnesota, United States

    20 investments

    Seed, Series A

    Biotech & Life Sciences, Climate & Energy, Healthcare

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    Vensana Capital logo

    Vensana Capital

    Minneapolis, Minnesota, United States

    17 investments

    Series A, Series D

    Healthcare, Biotech & Life Sciences

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    Piper Heartland Healthcare Capital logo

    Piper Heartland Healthcare Capital

    Minneapolis, Minnesota, United States

    12 investments

    Series C, Series B

    Healthcare

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    Deepwater Asset Management logo

    Deepwater Asset Management

    Minneapolis, Minnesota, United States

    10 investments

    Seed, Series A

    AI, Robotics & Automation, Hardware & Semiconductors

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    Allianz Life Ventures logo

    Allianz Life Ventures

    Minneapolis, Minnesota, United States

    9 investments

    Series B, Series C

    Insurance, Fintech, Enterprise Software

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    ECMC logo

    ECMC

    Minneapolis, Minnesota, United States

    9 investments

    Series A, Seed

    Education

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    Winslow Capital logo

    Winslow Capital

    Minneapolis, Minnesota, United States

    7 investments

    Series E, Series F

    Enterprise Software, Data & Analytics, Healthcare

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    Piper Sandler Merchant Banking logo

    Piper Sandler Merchant Banking

    Minneapolis, Minnesota, United States

    7 investments

    Series C, Series B

    Healthcare, Enterprise Software, Consumer

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    General Mills logo

    General Mills

    Minneapolis, Minnesota, United States

    7 investments

    Series B, Growth

    Food & Agriculture, Consumer

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    301 INC logo

    301 INC

    Minneapolis, Minnesota, United States

    7 investments

    Series B, Series A

    Food & Agriculture, Consumer

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    Frequently Asked Questions

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