Investment Firms in San Mateo, California, United States
Situated in the heart of Silicon Valley, it serves as a significant hub for venture capital, particularly for companies in the growth stages of Series A and Series B. The city's ecosystem is distinguished by its strong concentration on artificial intelligence, fintech, and biotechnology sectors. Its venture capital presence, largely established in the last two decades, benefits from deep integration with the broader regional network of innovation and talent.
San Mateo, California, United States's investment landscape is shaped by Fintech, with 48% of its 25 investment firms focused on this sector. The most active by portfolio size are Franklin Templeton, Draper Associates, and Boost VC.
Fintech dominates the investment landscape in San Mateo, with 48% of investment firms focused on this sector.
San Mateo has a long history of venture capital, with Franklin Templeton operating since 1947.
Last updated: 28 April 2026
Investment Firms
25
Total Investments
361
Top Sector
Fintech
Top Stage
Series A
Top Investment Sectors in San Mateo
The most popular sector focus among San Mateo investment firms is Fintech, with 12 investment firms (48%) investing in the space. This is followed by Cybersecurity (7), AI (7), Data & Analytics (5), Biotech & Life Sciences (5).
Investment Stages in San Mateo
San Mateo investment firms are most active at the Series A stage (13 investment firms). This is followed by Series B (12), Seed (12), Series C (9), Series D (4).
Franklin Templeton
San Mateo, California, United States
83 investments
Series E, Series B
Fintech, Enterprise Software, Data & Analytics …
Draper Associates
San Mateo, California, United States
70 investments
Seed, Series A
Biotech & Life Sciences, Defense & Space, Crypto & Web3 …
Boost VC
San Mateo, California, United States
33 investments
Seed, Series A
Defense & Space, Crypto & Web3, Fintech …
Celesta Capital
San Mateo, California, United States
31 investments
Series B, Series A
AI, Hardware & Semiconductors, Cybersecurity …
Semper Virens
San Mateo, California, United States
25 investments
Series A, Series B
Healthcare, PropTech, HR & Talent …
DNX
San Mateo, California, United States
20 investments
Series A, Series B
Cybersecurity, Robotics & Automation, Consumer …
GS Futures
San Mateo, California, United States
13 investments
Seed, Series A
Climate & Energy, HR & Talent, Gaming …
Draper Dragon
San Mateo, California, United States
12 investments
Seed, Series A
Crypto & Web3, AI, Gaming …
Inventus Capital
San Mateo, California, United States
11 investments
Series A, Series C
Healthcare, E-Commerce & Marketplace, Media & Entertainment …
Delphi Ventures
San Mateo, California, United States
10 investments
Seed, Series A
Crypto & Web3, AI, Gaming …
Recruit Strategic Partners
San Mateo, California, United States
7 investments
Series D, Series B
Fintech, Education, Developer Tools …
FalconX
San Mateo, California, United States
6 investments
Seed, Series D
Cybersecurity, Mobility & Transportation, Education …
Hercules
San Mateo, California, United States
5 investments
Series F, Growth
HR & Talent, Defense & Space, Robotics & Automation …
Mohr Davidow
San Mateo, California, United States
5 investments
Series B, Series A
Social & Community, Marketing & Advertising, Media & Entertainment …
SolarCity
San Mateo, California, United States
4 investments
Series C, Series B
Climate & Energy, Food & Agriculture
Union Labs
San Mateo, California, United States
4 investments
Series A, Seed
Robotics & Automation, Crypto & Web3, AI
Sempervirens Venture Capital
San Mateo, California, United States
4 investments
Series C, Series A
HR & Talent, Fintech
Peninsula Ventures
San Mateo, California, United States
4 investments
Series B, Series C
Data & Analytics, Cybersecurity, Fintech …
Fortitude Ventures
San Mateo, California, United States
3 investments
Consumer, Biotech & Life Sciences, Manufacturing
Guidewire Software
San Mateo, California, United States
2 investments
Fintech, PropTech
Roblox
San Mateo, California, United States
2 investments
Hardware & Semiconductors, Fintech
SurveyMonkey
San Mateo, California, United States
2 investments
SaaS, Fintech
Intercept
San Mateo, California, United States
2 investments
Cybersecurity
Freshworks
San Mateo, California, United States
2 investments
SaaS, Fintech
DraperDragon
San Mateo, California, United States
1 investments
Hardware & Semiconductors