Investment Firms in San Diego, California, United States
Known for its strong university research and established life sciences cluster, the region has developed a significant venture capital ecosystem. Its investment activity is particularly concentrated in healthcare and biotechnology, with growing emphasis on artificial intelligence and logistics. The ecosystem is characterized by a mature focus on early to mid-stage funding rounds, supporting companies as they scale from innovation to commercialization.
San Diego, California, United States's investment landscape is shaped by Biotech & Life Sciences, with 46% of its 13 investment firms focused on this sector. The most active by portfolio size are Qualcomm Ventures, Correlation Ventures, and Harpoon Ventures.
Biotech & Life Sciences dominates the investment landscape in San Diego, with 46% of investment firms focused on this sector.
San Diego is a particularly strong hub for early-stage investing, with over 92% of investment firms active at the Seed or Pre-Seed stage.
Last updated: 9 September 2026
Investment Firms
13
Total Investments
487
Top Sector
Biotech & Life Sciences
Top Stage
Series A
Top Investment Sectors in San Diego
The most popular sector focus among San Diego investment firms is Biotech & Life Sciences, with 6 investment firms (46%) investing in the space. This is followed by AI (5), Healthcare (5), Hardware & Semiconductors (4), Infrastructure & Cloud (4).
Investment Stages in San Diego
San Diego investment firms are most active at the Series A stage (12 investment firms). This is followed by Seed (12), Series B (8), Pre-Seed (7), Series C (6).
Qualcomm Ventures
San Diego, California, United States
193 investments
Series C, Series B
AI, Telecom, Mobility & Transportation …
Correlation Ventures
San Diego, California, United States
158 investments
Series A, Seed
AI, Biotech & Life Sciences, Consumer …
Harpoon Ventures
San Diego, California, United States
37 investments
Series A, Series B
AI, Cybersecurity, Defense & Space …
Boxer Capital of the Tavistock Group
San Diego, California, United States
32 investments
Series B, Series C
Biotech & Life Sciences
BioMed Ventures
San Diego, California, United States
17 investments
Series C, Series B
Biotech & Life Sciences, Healthcare
Behind Genius Ventures
San Diego, California, United States
12 investments
Seed, Pre Seed
AI, Enterprise Software, Consumer …
Radicle Growth
San Diego, California, United States
9 investments
Series A, Seed
Food & Agriculture, Climate & Energy, Biotech & Life Sciences …
NuFund Venture Group
San Diego, California, United States
8 investments
Seed, Series A
Enterprise Software, Healthcare, Biotech & Life Sciences …
Dexcom Ventures
San Diego, California, United States
5 investments
Series A, Series D
Healthcare, Biotech & Life Sciences
Seaside
San Diego, California, United States
5 investments
Seed, Series A
Construction, HR & Talent, Education …
L'ATTITUDE Ventures
San Diego, California, United States
4 investments
Seed, Series A
Fintech, SaaS, AI …
Keshif Ventures
San Diego, California, United States
4 investments
Seed, Series A
Data & Analytics, Enterprise Software, Infrastructure & Cloud
FusionX Ventures
San Diego, California, United States
3 investments
Series B, Series C
Hardware & Semiconductors, Infrastructure & Cloud, Healthcare …